Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling
about
Mechanism of activation for Zap-70 catalytic activityThe direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathwaysThe serine and threonine residues in the Ig-alpha cytoplasmic tail negatively regulate immunoreceptor tyrosine-based activation motif-mediated signal transductionSYK expression in human breast cancerCross-presentation of IgG-containing immune complexesB lymphocyte antigen receptor signaling: initiation, amplification, and regulationSHP-1 requires inhibitory co-receptors to down-modulate B cell antigen receptor-mediated phosphorylation of cellular substratesAssociation of SLP-65/BLNK with the B cell antigen receptor through a non-ITAM tyrosine of Ig-alphaSyk is required for BCR-mediated activation of p90Rsk, but not p70S6k, via a mitogen-activated protein kinase-independent pathway in B cellsSyk activation and dissociation from the B-cell antigen receptor is mediated by phosphorylation of tyrosine 130A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint InflammationPhosphorylation of Tyr342 in the linker region of Syk is critical for Fc epsilon RI signaling in mast cellsPhosphorylation of Syk activation loop tyrosines is essential for Syk function. An in vivo study using a specific anti-Syk activation loop phosphotyrosine antibodyThe Syk family of protein tyrosine kinases in T-cell activation and developmentTULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346, a Regulatory Site of SykEnhancement of B-cell receptor signaling by a point mutation of adaptor protein 3BP2 identified in human inherited disease cherubism.Tyrosine phosphorylation of 3BP2 regulates B cell receptor-mediated activation of NFATTwo distinct tyrosine-based motifs enable the inhibitory receptor FcgammaRIIB to cooperatively recruit the inositol phosphatases SHIP1/2 and the adapters Grb2/Grap.Stimulation of Src family protein-tyrosine kinases as a proximal and mandatory step for SYK kinase-dependent phospholipase Cgamma2 activation in lymphoma B cells exposed to low energy electromagnetic fields.Regulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3B cell activation triggered by the formation of the small receptor cluster: a computational study.B cell antigen receptor signaling and internalization are mutually exclusive events.The N-terminal SH2 domain of Syk is required for (hem)ITAM, but not integrin, signaling in mouse platelets.The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophilsComplex phosphorylation dynamics control the composition of the Syk interactome in B cells.Molecular underpinning of B-cell anergy.The conundrum of inhibitory signaling by ITAM-containing immunoreceptors: potential molecular mechanisms.Regulation of Syk by phosphorylation on serine in the linker insertB cell antigen receptor desensitization: disruption of receptor coupling to tyrosine kinase activationOf ITIMs, ITAMs, and ITAMis: revisiting immunoglobulin Fc receptor signaling.Ig beta tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization.Activation of Syk protein tyrosine kinase in response to osmotic stress requires interaction with p21-activated protein kinase Pak2/gamma-PAK.Multitasking of Ig-alpha and Ig-beta to regulate B cell antigen receptor function.Progress towards the development of SH2 domain inhibitors.Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation.Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy.Targeting Syk as a treatment for allergic and autoimmune disorders.syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction.A computational model for early events in B cell antigen receptor signaling: analysis of the roles of Lyn and Fyn.Matrix valency regulates integrin-mediated lymphoid adhesion via Syk kinase
P2860
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P2860
Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling
description
1995 nî lūn-bûn
@nan
1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Role of the Syk autophosphoryl ...... ell antigen receptor signaling
@ast
Role of the Syk autophosphoryl ...... ell antigen receptor signaling
@en
Role of the Syk autophosphoryl ...... ell antigen receptor signaling
@nl
type
label
Role of the Syk autophosphoryl ...... ell antigen receptor signaling
@ast
Role of the Syk autophosphoryl ...... ell antigen receptor signaling
@en
Role of the Syk autophosphoryl ...... ell antigen receptor signaling
@nl
prefLabel
Role of the Syk autophosphoryl ...... ell antigen receptor signaling
@ast
Role of the Syk autophosphoryl ...... ell antigen receptor signaling
@en
Role of the Syk autophosphoryl ...... ell antigen receptor signaling
@nl
P2093
P2860
P356
P1476
Role of the Syk autophosphoryl ...... ell antigen receptor signaling
@en
P2093
P2860
P304
P356
10.1084/JEM.182.6.1815
P407
P577
1995-12-01T00:00:00Z