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Survivin as a global target of intrinsic tumor suppression networks.

Survivin as a global target of intrinsic tumor suppression networks.

http://www.wikidata.org/entity/Q37589414

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Threonine 48 in the BIR domain of survivin is critical to its mitotic and anti-apoptotic activities and can be phosphorylated by CK2 in vitro Survivin - The inconvenient IAP Targeting survivin in cancer Genome-wide characterization of miR-34a induced changes in protein and mRNA expression by a combined pulsed SILAC and microarray analysis Omeprazole inhibits proliferation and modulates autophagy in pancreatic cancer cells Cavin-3 dictates the balance between ERK and Akt signaling.T-Type Ca2+ Channel Inhibition Sensitizes Ovarian Cancer to Carboplatin.Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced β-catenin/Tcf-Lef dependent transcription Immunohistochemical investigation of cell cycle and apoptosis regulators (survivin, β-catenin, p53, caspase 3) in canine appendicular osteosarcoma.Thimerosal-induced apoptosis in mouse C2C12 myoblast cells occurs through suppression of the PI3K/Akt/survivin pathway OCT4 positively regulates Survivin expression to promote cancer cell proliferation and leads to poor prognosis in esophageal squamous cell carcinoma.Absence of keratin 8 confers a paradoxical microflora-dependent resistance to apoptosis in the colon.Targeting survivin in cancer: novel drug development approaches.Function of survivin in trophoblastic cells of the placenta.Survivin is a novel target of CD44-promoted breast tumor invasion Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia.Survivin and IAP proteins in cell-death mechanisms Mechanisms of Trastuzumab resistance in ErbB2-driven breast cancer and newer opportunities to overcome therapy resistance.Phase I study of terameprocol in patients with recurrent high-grade glioma.Targeting Survivin Enhances Chemosensitivity in Retinoblastoma Cells and Orthotopic Tumors.Annonaceous acetogenins reverses drug resistance of human hepatocellular carcinoma BEL-7402/5-FU and HepG2/ADM cell lines Combined inhibition of Wee1 and Hsp90 activates intrinsic apoptosis in cancer cells Aberrant Alternative Polyadenylation is Responsible for Survivin Up-regulation in Ovarian Cancer Chk2 phosphorylation of survivin-DeltaEx3 contributes to a DNA damage-sensing checkpoint in cancer.Recently identified biomarkers that promote lymph node metastasis in head and neck squamous cell carcinoma Survivin as a Novel Biomarker in the Pathogenesis of Acne Vulgaris and Its Correlation to Insulin-Like Growth Factor-I.The relevance of the intrinsic subtype to the clinicopathological features and biomarkers in Japanese breast cancer patients.Apoptotic cell death in neuroblastoma.Functional genomics identify Birc5/survivin as a candidate gene involved in the chronotoxicity of cyclin-dependent kinase inhibitors.Caspases and cancer.Apoptosis: why and how does it occur in biology?Salmonella enterica as a vaccine carrier.Survivin (BIRC5) cell cycle computational network in human no-tumor hepatitis/cirrhosis and hepatocellular carcinoma transformation.Activation of CXCL12/CXCR4 renders colorectal cancer cells less sensitive to radiotherapy via up-regulating the expression of survivin.The involvement of survivin in insulin-like growth factor 1-induced epithelial-mesenchymal transition in gastric cancer.TGF-β Regulates Survivin to Affect Cell Cycle and the Expression of EGFR and MMP9 in Glioblastoma.RETRACTED: SDF-1/CXCR4 Axis Regulates Cell Cycle Progression and Epithelial-Mesenchymal Transition via Up-regulation of Survivin in Glioblastoma.Mdm2 antagonists induce apoptosis and synergize with cisplatin overcoming chemoresistance in TP53 wild-type ovarian cancer cells.Role of hypoxia-inducible factors in the dexrazoxane-mediated protection of cardiomyocytes from doxorubicin-induced toxicity.The prognostic significance of survivin expression in gallbladder carcinoma.

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Survivin as a global target of intrinsic tumor suppression networks.

http://www.wikidata.org/entity/Q37589414

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 07 September 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Survivin as a global target of intrinsic tumor suppression networks.

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Survivin as a global target of intrinsic tumor suppression networks.

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type

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Survivin as a global target of intrinsic tumor suppression networks.

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Survivin as a global target of intrinsic tumor suppression networks.

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prefLabel

Survivin as a global target of intrinsic tumor suppression networks.

@en

Survivin as a global target of intrinsic tumor suppression networks.

@nl

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Survivin as a global target of intrinsic tumor suppression networks.

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Dario C Altieri

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Minakshi Guha

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P2860

AKT/PKB signaling: navigating downstream

Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway

Aberrant regulation of survivin by the RB/E2F family of proteins

Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeutics

The cancer antiapoptosis mouse survivin gene: characterization of locus and transcriptional requirements of basal and cell cycle-dependent expression.

Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity.

Colonic crypt changes during adenoma development in familial adenomatous polyposis: immunohistochemical evidence for expansion of the crypt base cell population.

FoxOs at the crossroads of cellular metabolism, differentiation, and transformation.

The tumor suppressor Fhit acts as a repressor of beta-catenin transcriptional activity.

Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis.

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2708-2710

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scholarly article

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10.4161/CC.8.17.9457

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17

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19717980

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