The integrin alpha-subunit leg extends at a Ca2+-dependent epitope in the thigh/genu interface upon activation
about
Priming by chemokines restricts lateral mobility of the adhesion receptor LFA-1 and restores adhesion to ICAM-1 nano-aggregates on human mature dendritic cellsStructure of an integrin with an αI domain, complement receptor type 4Structural basis of integrin regulation and signalingBordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3Rolling on E- or P-selectin induces the extended but not high-affinity conformation of LFA-1 in neutrophilsHow the headpiece hinge angle is opened: New insights into the dynamics of integrin activation.Lateral mobility of individual integrin nanoclusters orchestrates the onset for leukocyte adhesionMultiple lupus-associated ITGAM variants alter Mac-1 functions on neutrophils.Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus.The wild boar (Sus scrofa) lymphocyte function-associated antigen-1 (CD11a/CD18) receptor: cDNA sequencing, structure analysis and comparison with homologuesMolecular mechanism of alpha2beta1 integrin interaction with human echovirus 1.Integrin α2β1 in nonactivated conformation can induce focal adhesion kinase signalingEpitope mapping for monoclonal antibody reveals the activation mechanism for αVβ3 integrin.AL-57, a ligand-mimetic antibody to integrin LFA-1, reveals chemokine-induced affinity up-regulation in lymphocytes.Organization of the integrin LFA-1 in nanoclusters regulates its activity.Identification, characterization, and epitope mapping of human monoclonal antibody J19 that specifically recognizes activated integrin α4β7.The regulation of integrin function by divalent cations.Regulation of immune cell adhesion and migration by regulator of adhesion and cell polarization enriched in lymphoid tissues.Integrin structures and conformational signalingIntegrin modulation and signaling in leukocyte adhesion and migration.The role of the integrin LFA-1 in T-lymphocyte migration.The leucocyte β2 (CD18) integrins: the structure, functional regulation and signalling properties.Evidence that monoclonal antibodies directed against the integrin beta subunit plexin/semaphorin/integrin domain stimulate function by inducing receptor extension.Solution properties of full-length integrin alpha(IIb)beta3 refined models suggest environment-dependent induction of alternative bent /extended resting states.Amino acid changes in Drosophila alphaPS2betaPS integrins that affect ligand affinity.In silico analysis of structural modifications in and around the integrin αIIb genu caused by ITGA2B variants in human platelets with emphasis on Glanzmann thrombasthenia.
P2860
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P2860
The integrin alpha-subunit leg extends at a Ca2+-dependent epitope in the thigh/genu interface upon activation
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 19 October 2004
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The integrin alpha-subunit leg ...... genu interface upon activation
@en
The integrin alpha-subunit leg ...... enu interface upon activation.
@nl
type
label
The integrin alpha-subunit leg ...... genu interface upon activation
@en
The integrin alpha-subunit leg ...... enu interface upon activation.
@nl
prefLabel
The integrin alpha-subunit leg ...... genu interface upon activation
@en
The integrin alpha-subunit leg ...... enu interface upon activation.
@nl
P2093
P2860
P356
P1476
The integrin alpha-subunit leg ...... genu interface upon activation
@en
P2093
Lloyd B Klickstein
Motomu Shimaoka
Pascale Schwab
Timothy A Springer
P2860
P304
15422-15427
P356
10.1073/PNAS.0406680101
P407
P577
2004-10-19T00:00:00Z