Immunogenicity and protection efficacy of replication-deficient influenza A viruses with altered NS1 genes. - Wikidata - wikimedia - TriplyDB

Immunogenicity and protection efficacy of replication-deficient influenza A viruses with altered NS1 genes.

Immunogenicity and protection efficacy of replication-deficient influenza A viruses with altered NS1 genes.

http://www.wikidata.org/entity/Q37596474

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Rotavirus NSP1 inhibits NFkappaB activation by inducing proteasome-dependent degradation of beta-TrCP: a novel mechanism of IFN antagonism Antiviral response in pandemic influenza viruses Making better influenza virus vaccines?Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus Induction of innate immunity and its perturbation by influenza viruses Preclinical evaluation of a replication-deficient intranasal DeltaNS1 H5N1 influenza vaccine Reverse Genetics Approaches for the Development of Influenza Vaccines Influenza A virus attenuation by codon deoptimization of the NS gene for vaccine development Sublingual immunization with a live attenuated influenza a virus lacking the nonstructural protein 1 induces broad protective immunity in mice Functional genomic and serological analysis of the protective immune response resulting from vaccination of macaques with an NS1-truncated influenza virus.The use of nonhuman primates in research on seasonal, pandemic and avian influenza, 1893-2014.Development of a vaccine against pandemic influenza viruses: current status and perspectives.Safety, immunogenicity and infectivity of new live attenuated influenza vaccines.Immunization with live attenuated influenza viruses that express altered NS1 proteins results in potent and protective memory CD8+ T-cell responses Innate immune evasion strategies of influenza viruses Human parainfluenza virus type 2 V protein inhibits interferon production and signaling and is required for replication in non-human primates.Recombinant human parainfluenza virus type 2 with mutations in V that permit cellular interferon signaling are not attenuated in non-human primates.Induction of CD8 T cell heterologous protection by a single dose of single-cycle infectious influenza virus.Vaccination of pigs against swine influenza viruses by using an NS1-truncated modified live-virus vaccine Animal Models for Influenza Virus Pathogenesis and Transmission.Influenza B virus NS1-truncated mutants: live-attenuated vaccine approach.Identification of human parainfluenza virus type 2 (HPIV-2) V protein amino acid residues that reduce binding of V to MDA5 and attenuate HPIV-2 replication in nonhuman primates Attenuated influenza virus construct with enhanced hemagglutinin protein expression Influenza virus partially counteracts restriction imposed by tetherin/BST-2.NS1-truncated live attenuated virus vaccine provides robust protection to aged mice from viral challenge.Broad influenza-specific CD8+ T-cell responses in humanized mice vaccinated with influenza virus vaccines.Blocking interhost transmission of influenza virus by vaccination in the guinea pig model.Respiratory and gastrointestinal epithelial modulation of the immune response during viral infection.Bunyaviruses and the type I interferon system.Live attenuated influenza virus expressing human interleukin-2 reveals increased immunogenic potential in young and aged hosts.Influenza C virus NS1 protein counteracts RIG-I-mediated IFN signalling.Influenza virus evades innate and adaptive immunity via the NS1 protein.Influenza viral vector based Brucella abortus vaccine: a novel vaccine candidate for veterinary practice.Mutations in the M-gene segment can substantially increase replication efficiency of NS1 deletion influenza A virus in MDCK cells.Influenza virus pathogenicity is determined by caspase cleavage motifs located in the viral proteins.Amelioration of influenza virus pathogenesis in chickens attributed to the enhanced interferon-inducing capacity of a virus with a truncated NS1 gene.The NS segment of H5N1 avian influenza viruses (AIV) enhances the virulence of an H7N1 AIV in chickens.Avian influenza virus NS1: A small protein with diverse and versatile functions.X-ray structure of influenza virus NS1 effector domain.Opinion of the Scientific Panel on Animal Health and Welfare (AHAW) related with the vaccination against avian influenza of H5 and H7 subtypes in domestic poultry and captive birds

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Immunogenicity and protection efficacy of replication-deficient influenza A viruses with altered NS1 genes.

http://www.wikidata.org/entity/Q37596474

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on December 2004

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Immunogenicity and protection ...... iruses with altered NS1 genes.

@en

Immunogenicity and protection ...... iruses with altered NS1 genes.

@nl

type

label

Immunogenicity and protection ...... iruses with altered NS1 genes.

@en

Immunogenicity and protection ...... iruses with altered NS1 genes.

@nl

prefLabel

Immunogenicity and protection ...... iruses with altered NS1 genes.

@en

Immunogenicity and protection ...... iruses with altered NS1 genes.

@nl

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JVI.78.23.13037-13045.2004

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Journal of Virology

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Immunogenicity and protection ...... viruses with altered NS1 genes

@en

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Andrej Egorov

http://www.w3.org/2001/XMLSchema#string

Christian Kittel

http://www.w3.org/2001/XMLSchema#string

Hermann Katinger

http://www.w3.org/2001/XMLSchema#string

Jana Stasakova

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Sabine Sereinig

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P2860

IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein

Influenza virus NS1 protein counteracts PKR-mediated inhibition of replication.

Cellular antiviral responses against influenza A virus are countered at the posttranscriptional level by the viral NS1A protein via its binding to a cellular protein required for the 3' end processing of cellular pre-mRNAS

A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice

Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza

Influenza virus still surprises.

Dynamic regulation of the proinflammatory cytokine, interleukin-1beta: molecular biology for non-molecular biologists.

The development of live attenuated cold-adapted influenza virus vaccine for humans.

Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein

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13037-13045

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scholarly article

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10.1128/JVI.78.23.13037-13045.2004

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2004-12-01T00:00:00Z

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15542655

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524997

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