Inactivation of the Mgat1 gene in oocytes impairs oogenesis, but embryos lacking complex and hybrid N-glycans develop and implant.
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Bridging the Gap between Glycosylation and Vesicle TrafficThe role of carbohydrate recognition during human sperm-egg bindingAgm1/Pgm3-mediated sugar nucleotide synthesis is essential for hematopoiesis and developmentZP2 and ZP3 traffic independently within oocytes prior to assembly into the extracellular zona pellucidaPremature ovarian failure in mice with oocytes lacking core 1-derived O-glycans and complex N-glycans.Recombinant porcine zona pellucida glycoproteins expressed in Sf9 cells bind to bovine sperm but not to porcine sperm.Fertilization: a sperm's journey to and interaction with the oocyte.A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans.Oocyte-targeted deletion reveals that hsp90b1 is needed for the completion of first mitosis in mouse zygotes.Complex N-glycans or core 1-derived O-glycans are not required for the expression of stage-specific antigens SSEA-1, SSEA-3, SSEA-4, or Le(Y) in the preimplantation mouse embryoCanonical Notch signaling is dispensable for early cell fate specifications in mammalsThe expression pattern of microRNAs in granulosa cells of subordinate and dominant follicles during the early luteal phase of the bovine estrous cycleMouse fertility is enhanced by oocyte-specific loss of core 1-derived O-glycans.Molecular analysis of the cumulus matrix: insights from mice with O-glycan-deficient oocytes.Gamete recognition in mice depends on the cleavage status of an egg's zona pellucida protein.Human ZP4 is not sufficient for taxon-specific sperm recognition of the zona pellucida in transgenic mice.Human sperm bind to the N-terminal domain of ZP2 in humanized zonae pellucidae in transgenic mice.Complex N-glycans are essential, but core 1 and 2 mucin O-glycans, O-fucose glycans, and NOTCH1 are dispensable, for mammalian spermatogenesisGenome-Wide Association Study for Indicator Traits of Sexual Precocity in Nellore Cattle.Structural insights into the interaction of human IgG1 with FcγRI: no direct role of glycans in binding.Embryos generated from oocytes lacking complex N- and O-glycans have compromised development and implantation.Molecular models for murine sperm-egg binding.In vivo consequences of deleting EGF repeats 8-12 including the ligand binding domain of mouse Notch1.The molecular basis of gamete recognition in mice and humansProtein O-GlcNAcylation is required for fibroblast growth factor signaling in Drosophila.Cellular mechanisms regulating sperm-zona pellucida interaction.ART failure: oocyte contributions to unsuccessful fertilization.Reassessing the role of protein-carbohydrate complementarity during sperm-egg interactions in the mouse.Classical galactosaemia: novel insights in IgG N-glycosylation and N-glycan biosynthesis.N-glycosylation requirements in neuromuscular synaptogenesis.Dysregulation of follicle development in a mouse model of premature ovarian insufficiency.Oocyte-specific deletion of complex and hybrid N-glycans leads to defects in preovulatory follicle and cumulus mass developmentThe mammalian zona pellucida: a matrix that mediates both gamete binding and immune recognition?What Have We Learned from Glycosyltransferase Knockouts in Mice?Classical Galactosaemia and CDG, the N-Glycosylation Interface. A Review.Structures and developmental alterations of N-glycans of zebrafish embryos.Recombinant bovine zona pellucida glycoproteins ZP3 and ZP4 coexpressed in Sf9 cells form a sperm-binding active hetero-complex.Formation of multiple-oocyte follicles in culture.The TGF-β inhibitory activity of antibody 37E1B5 depends on its H-CDR2 glycan.MGAT1 and Complex N-Glycans Regulate ERK Signaling During Spermatogenesis.
P2860
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P2860
Inactivation of the Mgat1 gene in oocytes impairs oogenesis, but embryos lacking complex and hybrid N-glycans develop and implant.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
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2004年學術文章
@zh-hant
name
Inactivation of the Mgat1 gene ...... N-glycans develop and implant.
@en
Inactivation of the Mgat1 gene ...... N-glycans develop and implant.
@nl
type
label
Inactivation of the Mgat1 gene ...... N-glycans develop and implant.
@en
Inactivation of the Mgat1 gene ...... N-glycans develop and implant.
@nl
prefLabel
Inactivation of the Mgat1 gene ...... N-glycans develop and implant.
@en
Inactivation of the Mgat1 gene ...... N-glycans develop and implant.
@nl
P2093
P2860
P1476
Inactivation of the Mgat1 gene ...... N-glycans develop and implant
@en
P2093
Antti Seppo
Henry Kurniawan
Jamey D Marth
Pamela Stanley
Shaolin Shi
Zhengyi Ye
P2860
P304
P356
10.1128/MCB.24.22.9920-9929.2004
P407
P577
2004-11-01T00:00:00Z