Tankyrase polymerization is controlled by its sterile alpha motif and poly(ADP-ribose) polymerase domains.
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Tankyrase-1 assembly to large protein complexes blocks its telomeric functionWnt/beta-catenin signaling and small molecule inhibitorsCrystal structure of a Tankyrase-Axin complex and its implications for Axin turnover and Tankyrase substrate recruitmentEvaluation and Structural Basis for the Inhibition of Tankyrases by PARP InhibitorsTankyrase Sterile α Motif Domain Polymerization Is Required for Its Role in Wnt SignalingTankyrase Inhibitors Stimulate the Ability of Tankyrases to Bind Axin and Drive Assembly of β-Catenin Degradation-Competent Axin PunctaTankyrase 2 poly(ADP-ribose) polymerase domain-deleted mice exhibit growth defects but have normal telomere length and cappingUbiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signalingNuMA is a major acceptor of poly(ADP-ribosyl)ation by tankyrase 1 in mitosis.Tankyrase1-mediated poly(ADP-ribosyl)ation of TRF1 maintains cell survival after telomeric DNA damage.A human sterile alpha motif domain polymerizome.Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs.Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity.Poly(ADP-ribosylation) and genomic stability.Adapter protein connections: the MRL and Grb7 protein families.The telomeric PARP, tankyrases, as targets for cancer therapyStructural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling.Tankyrases as drug targets.A role for synaptic zinc in ProSAP/Shank PSD scaffold malformation in autism spectrum disorders.Tankyrases: structure, function and therapeutic implications in cancer.Tankyrase recruitment to the lateral membrane in polarized epithelial cells: regulation by cell-cell contact and protein poly(ADP-ribosyl)ationTargeting Tankyrase to Fight WNT-dependent Tumours.Poly(ADP-ribosyl)ation of mannose-binding lectin out of human kidney cells.Structural insights into SAM domain-mediated tankyrase oligomerization.Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-β-Catenin Signaling.USP25 regulates Wnt signaling by controlling the stability of tankyrases.The PARsylation activity of tankyrase in adipose tissue modulates systemic glucose metabolism in mice.Whole proteome analysis of human tankyrase knockout cells reveals targets of tankyrase-mediated degradation.Regulation of Wnt/β-catenin signalling by tankyrase-dependent poly(ADP-ribosyl)ation and scaffolding.Structural basis for tankyrase-RNF146 interaction reveals noncanonical tankyrase-binding motifs.Cross-species difference in telomeric function of tankyrase 1.
P2860
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P2860
Tankyrase polymerization is controlled by its sterile alpha motif and poly(ADP-ribose) polymerase domains.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
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2004年學術文章
@zh-hant
name
Tankyrase polymerization is controlled by its sterile alpha motif and poly
@nl
Tankyrase polymerization is co ...... DP-ribose) polymerase domains.
@en
type
label
Tankyrase polymerization is controlled by its sterile alpha motif and poly
@nl
Tankyrase polymerization is co ...... DP-ribose) polymerase domains.
@en
prefLabel
Tankyrase polymerization is controlled by its sterile alpha motif and poly
@nl
Tankyrase polymerization is co ...... DP-ribose) polymerase domains.
@en
P2860
P1476
Tankyrase polymerization is co ...... DP-ribose) polymerase domains.
@en
P2093
Carolyn M Price
Manu De Rycker
P2860
P304
P356
10.1128/MCB.24.22.9802-9812.2004
P407
P577
2004-11-01T00:00:00Z