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Structure prediction and validation of the ERK8 kinase domainMultiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformationMolecular cloning and expression analysis of the human Rab7 GTP-ase complementary deoxyribonucleic acidRab5a is a common component of the apical and basolateral endocytic machinery in polarized epithelial cellsThe small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathwayGenetic mapping of the mouse Rab7 gene and pseudogene and of the human RAB7 homolog.Interaction cloning and characterization of the cDNA encoding the human prenylated rab acceptor (PRA1).Extracellular signal-regulated kinase 8 (ERK8) controls estrogen-related receptor α (ERRα) cellular localization and inhibits its transcriptional activity.Activation of the Erk8 mitogen-activated protein (MAP) kinase by RET/PTC3, a constitutively active form of the RET proto-oncogene.Regulation of gene expression by the small GTPase Rho through the ERK6 (p38 gamma) MAP kinase pathway.Discovery of 14-3-3 protein-protein interaction inhibitors that sensitize multidrug-resistant cancer cells to doxorubicin and the Akt inhibitor GSK690693.Aptamer targeting EGFRvIII mutant hampers its constitutive autophosphorylation and affects migration, invasion and proliferation of glioblastoma cells.One drug for two targets: Biological evaluation of antiretroviral agents endowed with antiproliferative activity.MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation.Cloning and expression analysis of the murine Rab7 cDNA.MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors.Growth factor transduction pathways: paradigm of anti-neoplastic targeted therapy.Improvement of pyrazolo[3,4-d]pyrimidines pharmacokinetic properties: nanosystem approaches for drug delivery.Prodrugs of Pyrazolo[3,4-d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model.Pyrazolo[3,4-d]pyrimidines-loaded human serum albumin (HSA) nanoparticles: Preparation, characterization and cytotoxicity evaluation against neuroblastoma cell line.Aptamer Functionalization of Nanosystems for Glioblastoma Targeting through the Blood-Brain Barrier.Identification of new pyrrolo[2,3-d]pyrimidines as Src tyrosine kinase inhibitors in vitro active against Glioblastoma.Straightforward synthesis of a novel ring-fused pyrazole-lactam and in vitro cytotoxic activity on cancer cell lines.NCOA4 Deficiency Impairs Systemic Iron Homeostasis.The small GTP-binding protein RhoA regulates c-jun by a ROCK-JNK signaling axis.Role of the small GTPase Rab7 in the late endocytic pathway.Context-dependent miR-204 and miR-211 affect the biological properties of amelanotic and melanotic melanoma cells.Selective transcription and cellular proliferation induced by PDGF require histone deacetylase activity.Regulation of mitogen-activated protein kinases by G-protein-coupled receptors.Regulation of c-myc expression by PDGF through Rho GTPases.The platelet-derived growth factor controls c-myc expression through a JNK- and AP-1-dependent signaling pathway.EGFR-Targeted Magnetic Nanovectors Recognize, in Vivo, Head and Neck Squamous Cells Carcinoma-Derived Tumors.Alterations of autophagy in the peripheral neuropathy Charcot-Marie-Tooth type 2B.Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions. Evidence for the association of phosphatidylinositol 3-kinase with the E-cadherin adhesion complex.Surface chemistry and entrapment of magnesium nanoparticles into polymeric micelles: a highly biocompatible tool for photothermal therapyActivated kinase screening identifies the IKBKE oncogene as a positive regulator of autophagyMAPK15 is part of the ULK complex and controls its activity to regulate early phases of the autophagic processMolecular insights to the bioactive form of BV02, a reference inhibitor of 14-3-3σ protein-protein interactionsGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction
P50
Q21090822-2228A47F-C614-42E6-96C1-1819B1DDF3EFQ24554295-3333A559-F220-4849-9BDC-8EF0196E5C60Q28116614-272BC822-4407-4AD8-9E14-309414C7D747Q28509305-148D9BC7-C7C4-4431-8CDB-F77E9AEE57CBQ29614258-EEB4B18B-550D-4704-BF6C-831273570266Q32064271-5F6CBB70-E9F0-453D-8ED3-321F127F498EQ33862232-F9703F5D-F91D-45B4-9C48-AD1BECE16A34Q34156903-7488DDE4-61A8-43DC-90BE-FC633F715891Q34495337-AA6D13B8-5E3D-4169-8191-18CAC2AA07B9Q35077234-FD4E1792-FA32-4642-932F-84976EFFB411Q35143276-6407BE50-0CC9-4BDB-ACD9-85ACCD81724FQ35804765-22E4E058-228B-49CA-806F-4FE6D919F77BQ36346462-56317BA7-3D76-449F-BBD9-300EC9FC2BE8Q36777169-07C91978-E54C-4586-AD42-D7ED6302305BQ36789530-AF81D8D1-5F1A-4AE7-B4D8-41CB68222E4CQ37190502-D237EFDE-4E08-4194-932C-55FF5A7563D6Q38218298-80382736-8292-4960-A18F-342AA917411DQ38582337-FEE26151-F930-4219-9A0C-F089CDC5C1BFQ38699033-E06841BF-F7D4-4D64-B22E-D1029E8A1F7AQ38701836-864CFC0A-23ED-452C-BCA8-10FFF8A298F8Q38704878-EE5590E0-3ED7-4C94-8D8F-7F2710ACCD65Q38721884-1D68E581-6ADA-4353-ADA5-ACC25B54668CQ38778074-64103BE2-4641-4A37-86BB-AE166A7A7E92Q38802658-DC95A431-76E8-43FE-BAE1-90B06C558C5CQ40569386-B9F66BD8-E577-421F-9A72-118D010279A5Q41127805-B5C90129-071C-4EB7-AC89-7598BA66DB42Q41862341-34BDCAB2-B081-4A57-B89D-5A7622A8ABDEQ42804078-8C3050CE-263F-41B6-84F2-A282F0202467Q42824479-8C646FF6-0DC8-40D6-BD0D-B8BD7D52F444Q42828450-4BF960C1-C12B-469B-ACAA-2FA0EC72CA79Q42835267-03C6AB53-4B87-4141-B3EA-8171DBE822DDQ47772716-BC12BDCC-CCE6-4435-8AB8-B6926FA92E59Q50052628-010AC023-3B3B-4651-B0B4-5B7D96397937Q52176221-7242BE1A-0C1A-45A3-BB2B-E7FEE6FB8010Q56973616-680FF56F-C9FF-4580-9233-98A769B01DD2Q56978683-FDAA4E8A-3AD7-4DC8-99ED-D003293075DEQ57168286-47EDB6F4-3F78-41CA-BF9C-F89E789122A2Q87093998-4519D5F6-E701-4507-A62A-4B49B32D94DBQ87139132-22B4C7F3-498A-4B28-B7C7-D52682077BA7Q90108261-A4648360-BAF8-4CCC-BF84-7DD911EEAED8
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Mario Chiariello
@ast
Mario Chiariello
@en
Mario Chiariello
@es
Mario Chiariello
@nl
Mario Chiariello
@sl
type
label
Mario Chiariello
@ast
Mario Chiariello
@en
Mario Chiariello
@es
Mario Chiariello
@nl
Mario Chiariello
@sl
prefLabel
Mario Chiariello
@ast
Mario Chiariello
@en
Mario Chiariello
@es
Mario Chiariello
@nl
Mario Chiariello
@sl
P108
P1053
O-3642-2014
P106
P108
P1153
7101962941
P21
P31
P3829
P496
0000-0001-8434-5177