The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
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Activation of Rac1 by a Crk SH3-binding protein, DOCK180PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodiaCloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPasesA novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to RhoNSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathwayhSiah2 is a new Vav binding protein which inhibits Vav-mediated signaling pathwaysMSE55, a Cdc42 effector protein, induces long cellular extensions in fibroblastsHuman JIK, a novel member of the STE20 kinase family that inhibits JNK and is negatively regulated by epidermal growth factorGene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions, such as diabetic nephropathy. Possible role in the response to persistent streCdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylationSPECs, small binding proteins for Cdc42Cdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actinThe hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory functionA novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signalingA conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPasesFibroblast growth factor homologous factors and the islet brain-2 scaffold protein regulate activation of a stress-activated protein kinaseICAP-1, a novel beta1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta1 integrinNuclear Rho kinase, ROCK2, targets p300 acetyltransferaseA human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathwaysThe multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domainsHPK1, a hematopoietic protein kinase activating the SAPK/JNK pathwayDirect activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 (MEKK) derivativeMADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinaseMyotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganizationSelective interaction of JNK protein kinase isoforms with transcription factorsA CD317/tetherin-RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cellsIn vitro enhancement of p38 mitogen-activated protein kinase activity by phosphorylated glia maturation factorA new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesionHuman mitogen-activated protein kinase kinase 7 (MKK7) is a highly conserved c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) activated by environmental stresses and physiological stimuliMolecular cloning and functional expression of a cDNA encoding a new member of mixed lineage protein kinase from human brainIQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42HsCrystal structure of a small G protein in complex with the GTPase-activating protein rhoGAPIdentification of a novel Rac1-interacting protein involved in membrane rufflingIdentification of a novel guanine nucleotide exchange factor for the Rho GTPaseActivation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinaseTranscriptional repressor ERF is a Ras/mitogen-activated protein kinase target that regulates cellular proliferation.CDC42 and FGD1 cause distinct signaling and transforming activities.Interaction of Nck-associated protein 1 with activated GTP-binding protein RacThe MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways
P2860
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P2860
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The small GTP-binding proteins ...... the JNK/SAPK signaling pathway
@ast
The small GTP-binding proteins ...... the JNK/SAPK signaling pathway
@en
type
label
The small GTP-binding proteins ...... the JNK/SAPK signaling pathway
@ast
The small GTP-binding proteins ...... the JNK/SAPK signaling pathway
@en
prefLabel
The small GTP-binding proteins ...... the JNK/SAPK signaling pathway
@ast
The small GTP-binding proteins ...... the JNK/SAPK signaling pathway
@en
P2093
P50
P3181
P1433
P1476
The small GTP-binding proteins ...... the JNK/SAPK signaling pathway
@en
P2093
P304
P3181
P356
10.1016/S0092-8674(05)80018-2
P407
P577
1995-06-01T00:00:00Z