Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma.
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The chromosomal location of T-cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T cell leukaemiaThe human mdr3 gene encodes a novel P-glycoprotein homologue and gives rise to alternatively spliced mRNAs in liverActivation of the pp60c-src protein kinase is an early event in colonic carcinogenesisHuman prostate tumor growth in athymic mice: inhibition by androgens and stimulation by finasteridepp60c-src activation in human colon carcinomaNucleotide sequence of the 3' exon of the human N-myc geneCloning of the esterase D gene: a polymorphic gene probe closely linked to the retinoblastoma locus on chromosome 13Nucleotide sequence of the human N-myc geneThe PVT gene frequently amplifies with MYC in tumor cellsIsolation of monoclonal antibodies specific for human c-myc proto-oncogene productDNA tetraplex formation in the control region of c-mycRole of DLC1 tumor suppressor gene and MYC oncogene in pathogenesis of human hepatocellular carcinoma: potential prospects for combined targeted therapeutics (review)Human U1 small nuclear RNA genes: extensive conservation of flanking sequences suggests cycles of gene amplification and transpositionIsolation of the amplified dihydrofolate reductase domain from methotrexate-resistant Chinese hamster ovary cells.Functional analysis of c-Myb protein in T-lymphocytic cell lines shows that it trans-activates the c-myc promoterThe dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure.Organization and genesis of dihydrofolate reductase amplicons in the genome of a methotrexate-resistant Chinese hamster ovary cell line.The mouse surfeit locus contains a very tight cluster of four "housekeeping" genes that is conserved through evolutionAmplified human MYC oncogenes localized to replicating submicroscopic circular DNA molecules.The short arm of chromosome 11 is a "hot spot" for hypermethylation in human neoplasiaPatterns of mRNA expression during early cell growth differ in kidney epithelial cells destined to undergo compensatory hypertrophy versus regenerative hyperplasia.Altered growth of a human neuroendocrine carcinoma line after transfection of a major histocompatibility complex class I gene.Evidence that the familial adenomatous polyposis gene is involved in a subset of colon cancers with a complementable defect in c-myc regulation.Intragenic pausing and anti-sense transcription within the murine c-myc locusChromatin structure of the murine c-myc locus: implications for the regulation of normal and chromosomally translocated genes.Transformation of mammalian fibroblasts and macrophages in vitro by a murine retrovirus encoding an avian v-myc oncogene.Astrocyte growth is regulated by neuropeptides through Tis 8 and basic fibroblast growth factorMolecular inversion probe analysis of gene copy alterations reveals distinct categories of colorectal carcinomaNovel functional MAR elements of double minute chromosomes in human ovarian cells capable of enhancing gene expression.XB130, a novel adaptor protein, promotes thyroid tumor growth.Loss of the MYC gene amplified in human HL-60 cells after treatment with inhibitors of poly(ADP-ribose) polymerase or with dimethyl sulfoxide.XB130, a new adaptor protein, regulates expression of tumor suppressive microRNAs in cancer cells.Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification.Clinical implications of the cancer genomeIn vivo differentiation of blast-phase chronic granulocytic leukemia. Expression of c-myc and c-abl protooncogenes.myc family oncogene amplification in tumor cell lines established from small cell lung cancer patients and its relationship to clinical status and course.Evolutionarily conserved regions of the human c-myc protein can be uncoupled from transforming activity.Papillomavirus sequences integrate near cellular oncogenes in some cervical carcinomas.Mitotic recombination between homologous chromosomes generates H-2 somatic cell variants in vitro.Activation of pp60c-src protein kinase activity in human colon carcinoma.
P2860
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P2860
Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 1983
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Homogeneously staining chromos ...... from a human colon carcinoma.
@en
Homogeneously staining chromos ...... ly expressed cellular oncogene
@nl
type
label
Homogeneously staining chromos ...... from a human colon carcinoma.
@en
Homogeneously staining chromos ...... ly expressed cellular oncogene
@nl
prefLabel
Homogeneously staining chromos ...... from a human colon carcinoma.
@en
Homogeneously staining chromos ...... ly expressed cellular oncogene
@nl
P2093
P2860
P356
P1476
Homogeneously staining chromos ...... from a human colon carcinoma.
@en
P2093
P2860
P304
P356
10.1073/PNAS.80.6.1707
P407
P577
1983-03-01T00:00:00Z