Monoclonal antibody-targeted superantigens: a different class of anti-tumor agents.
about
Characterization of tissue-specific LIM domain protein (FHL1C) which is an alternatively spliced isoform of a human LIM-only protein (FHL1)Human TGFalpha-derived peptide TGFalphaL3 fused with superantigen for immunotherapy of EGFR-expressing tumours.The tumor targeted superantigen ABR-217620 selectively engages TRBV7-9 and exploits TCR-pMHC affinity mimicry in mediating T cell cytotoxicity.Disulfide-stabilized single-chain antibody-targeted superantigen: construction of a prokaryotic expression system and its functional analysis.Immunological response and overall survival in a subset of advanced renal cell carcinoma patients from a randomized phase 2/3 study of naptumomab estafenatox plus IFN-α versus IFN-α.Monoclonal antibody-superantigen fusion proteins: tumor-specific agents for T-cell-based tumor therapy.Genetically engineered superantigens as tolerable antitumor agents.Preparation and activity of conjugate of monoclonal antibody HAb18 against hepatoma F(ab')(2) fragment and staphylococcal enterotoxin A.A phase II study of a 5T4 oncofoetal antigen tumour-targeted superantigen (ABR-214936) therapy in patients with advanced renal cell carcinoma.Therapy of human non-small-cell lung carcinoma using antibody targeting of a modified superantigen.SEA antagonizes the imatinib-meditated inhibitory effects on T cell activation via the TCR signaling pathwayMajor histocompatibility complex class I molecule serves as a ligand for presentation of the superantigen staphylococcal enterotoxin B to T cells.Naptumomab estafenatox: targeted immunotherapy with a novel immunotoxinSensitization of tumour cells to lysis by virus-specific CTL using antibody-targeted MHC class I/peptide complexes.Preparation and in-vitro bioactivity of a novel superantigen conjugate targeting bladder carcinoma.Bacterial pyrogenic exotoxins as superantigens.Polyethylenimine-mediated in vivo gene transfer of a transmembrane superantigen fusion construct inhibits B16 murine melanoma growth.Gene therapy by membrane-expressed superantigen for alpha-fetoprotein-producing hepatocellular carcinoma.Targeting of superantigens.The crystal structure of staphylococcal enterotoxin type D reveals Zn2+-mediated homodimerization.Targeting of drugs to cell surface receptors.Primary cytotoxicity of SEB-activated human PBMC and separated CD8+ and CD4+ T lymphocytes elicited by two different stimulation protocols.Prevention of lung metastasis by intra-tumoral injection of Cepharanthin and staphylococcal enterotoxin B in transplantable rat osteosarcoma.Identification of framework residues in a secreted recombinant antibody fragment that control production level and localization in Escherichia coli.
P2860
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P2860
Monoclonal antibody-targeted superantigens: a different class of anti-tumor agents.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Monoclonal antibody-targeted superantigens: a different class of anti-tumor agents.
@en
Monoclonal antibody-targeted superantigens: a different class of anti-tumor agents.
@nl
type
label
Monoclonal antibody-targeted superantigens: a different class of anti-tumor agents.
@en
Monoclonal antibody-targeted superantigens: a different class of anti-tumor agents.
@nl
prefLabel
Monoclonal antibody-targeted superantigens: a different class of anti-tumor agents.
@en
Monoclonal antibody-targeted superantigens: a different class of anti-tumor agents.
@nl
P2093
P2860
P356
P1476
Monoclonal antibody-targeted superantigens: a different class of anti-tumor agents.
@en
P2093
P2860
P304
P356
10.1073/PNAS.88.20.9287
P407
P577
1991-10-01T00:00:00Z