Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain.
about
It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer DiseaseThe Janus face of the heme oxygenase/biliverdin reductase system in Alzheimer disease: it's time for reconciliationThe 2013 SFRBM discovery award: selected discoveries from the butterfield laboratory of oxidative stress and its sequela in brain in cognitive disorders exemplified by Alzheimer disease and chemotherapy induced cognitive impairmentElevated risk of type 2 diabetes for development of Alzheimer disease: a key role for oxidative stress in brainNeuronal failure in Alzheimer's disease: a view through the oxidative stress looking-glassTraditional Chinese Nootropic Medicine Radix Polygalae and Its Active Constituent Onjisaponin B Reduce β-Amyloid Production and Improve Cognitive ImpairmentsRedox proteomics analysis to decipher the neurobiology of Alzheimer-like neurodegeneration: overlaps in Down's syndrome and Alzheimer's disease brain.The burden of trisomy 21 disrupts the proteostasis network in Down syndrome.Memory decline in Down syndrome and its relationship to iPF2alpha, a urinary marker of oxidative stressNeuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain.Bach1 overexpression in Down syndrome correlates with the alteration of the HO-1/BVR-a system: insights for transition to Alzheimer's disease.Redox proteomics analysis of HNE-modified proteins in Down syndrome brain: clues for understanding the development of Alzheimer disease.Essential role of proteasomes in maintaining self-renewal in neural progenitor cells.Aging in Down Syndrome and the Development of Alzheimer's Disease Neuropathology.Clinical implications from proteomic studies in neurodegenerative diseases: lessons from mitochondrial proteins.Activation of p53 in Down Syndrome and in the Ts65Dn Mouse Brain is Associated with a Pro-Apoptotic Phenotype.Unraveling the complexity of neurodegeneration in brains of subjects with Down syndrome: insights from proteomics.Targeting mTOR to reduce Alzheimer-related cognitive decline: from current hits to future therapies.The Role of Cathepsin D in the Pathogenesis of Human Neurodegenerative Disorders.The fine-tuning of proteolytic pathways in Alzheimer's disease.Proteomic profile of serum of pregnant women carring a fetus with Down syndrome using nano uplc Q-tof ms/ms technology.Insulin signalling in Alzheimer's disease and diabetes: from epidemiology to molecular links.Increased non-protein bound iron in Down syndrome: contribution to lipid peroxidation and cognitive decline.A Comprehensive Diverse '-omics' Approach to Better Understanding the Molecular Pathomechanisms of Down Syndrome.Disturbance of redox homeostasis in Down Syndrome: Role of iron dysmetabolism.Aβ42-mediated proteasome inhibition and associated tau pathology in hippocampus are governed by a lysosomal response involving cathepsin B: Evidence for protective crosstalk between protein clearance pathways.NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease.Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD.mTOR in Down syndrome: Role in Aß and tau neuropathology and transition to Alzheimer disease-like dementia.Down syndrome, beta-amyloid and neuroimaging.Polyubiquitinylation Profile in Down Syndrome Brain Before and After the Development of Alzheimer Neuropathology.Dysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease.Early and Selective Activation and Subsequent Alterations to the Unfolded Protein Response in Down Syndrome Mouse Models.When nature's robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human aging disease pathologies.Cathepsin D as a therapeutic target in Alzheimer's disease.A proteomic approach reveals the differential protein expression in Drosophila melanogaster treated with red ginseng extract (Panax ginseng).Early Life Stress and Epigenetics in Late-onset Alzheimer's Dementia: A Systematic ReviewIntranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndromeOxidative Stress and Proteostasis Network: Culprit and Casualty of Alzheimer’s-Like Neurodegeneration
P2860
Q26765816-5143D660-6E8B-4D9A-A5D2-F41DF3769ACBQ26823454-2F242243-28A9-418F-8D6B-4CB306C00AF4Q26827320-8679EEEF-394D-46B2-A483-DE80602A2481Q27003253-C4C1AB19-2D97-427D-A91E-A1BBB606B71EQ27015785-ABABAA08-21F1-4109-BEBD-5A6DDA0F6425Q28550590-323674F1-A147-49D9-AA59-BA51CCA2A2D2Q30367032-B216D701-B202-4E10-B5D3-B789C23BB760Q33590361-D86F06C1-2B9B-4C0C-906E-98023DC2B40DQ33716691-4E41C39D-3DC5-4DD9-B7DA-2CF9D0C3E252Q33775384-DC1DF412-560F-4454-9928-FE13A51FF6C7Q36367840-D40843F9-5801-4A2C-970D-1580E9DBABEBQ36390685-2E7B12A3-B976-45D0-A1DB-B523D1CCF047Q36501223-AC594CEF-94CB-497D-878B-D0E5B028E113Q37102001-F8C9841D-EA1F-470B-94B6-76F7983E4595Q37105161-6502FFC4-F7C5-4D50-BBFC-62CB674C0498Q37141585-B12712EC-2FE4-4750-B034-A1096FF9FC62Q37662773-47112869-BF19-4107-AB25-2D148AF52C84Q38815881-F7103139-99A5-4E08-9474-2C56DF0B5AD7Q38817664-8E1ECF4E-9206-415A-AF50-F15F69C72DC7Q38819083-57B3432C-D222-4366-9C18-3142AF963C6BQ38835303-C5B094D2-6C9C-48F3-87DE-5B274463F323Q38980167-E05845E8-94EB-46CF-A9C2-72D0F71579B9Q39244955-0D11C06A-854E-4FB0-AA98-3ED231642CFBQ39254480-5FD30A7A-1637-471B-8304-406D9CC2F3C6Q39433562-58F67DC6-26FB-415E-B825-5EEE3391AC6EQ41348866-3F9B4651-57CE-4C1E-A474-7D26CAF3691CQ41427586-1DC0B8D2-8382-4C99-8DB9-DE95B4970FB8Q46778500-A7428DFC-96A0-4A65-9445-9F5C9C01B472Q47953822-6AE0461C-580B-4470-A0D1-BE8BA612BAE3Q48102481-46FA9637-C7F0-4BDE-8D49-641D4364E359Q48513955-BD15ED27-B915-433B-BEC4-9362B388CECDQ49497621-4411C6BB-C779-4BE6-A220-9A94D61B3A84Q50034506-1F175249-E31D-4F63-AE5D-B7BAC11BC283Q51763128-F71E12AA-E630-4110-B819-D4A19B396289Q53383359-39C7B37B-7A04-44D9-952F-8D02908C6EC9Q55437118-8B28D052-FB1B-4C3F-8451-BED0FBEE391EQ58549216-B891693D-8BD4-40D4-9D83-9619017B8856Q58609012-2F2FD579-C131-4542-83DE-2D9CCF68430AQ59049869-9C86C21E-0C7D-427F-AE6A-989C87A1F8C0
P2860
Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 18 April 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Impairment of proteostasis net ...... omics analysis of human brain.
@en
Impairment of proteostasis net ...... omics analysis of human brain.
@nl
type
label
Impairment of proteostasis net ...... omics analysis of human brain.
@en
Impairment of proteostasis net ...... omics analysis of human brain.
@nl
prefLabel
Impairment of proteostasis net ...... omics analysis of human brain.
@en
Impairment of proteostasis net ...... omics analysis of human brain.
@nl
P2093
P2860
P50
P1476
Impairment of proteostasis net ...... eomics analysis of human brain
@en
P2093
Alessandra Giorgi
Annalisa Cocciolo
D Allan Butterfield
Elizabeth Head
M Paul Murphy
Maria Eugenia Schinina
Marzia Perluigi
P2860
P304
P356
10.1016/J.BBADIS.2013.04.013
P407
P577
2013-04-18T00:00:00Z