Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time.
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T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in miceA THEMIS:SHP1 complex promotes T-cell survivalAn induced rebinding model of antigen discriminationAction and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological SynapseMathematics in modern immunologyUltrasensitivity in the Cofilin Signaling Module: A Mechanism for Tuning T Cell ResponsesIdentifying Individual T Cell Receptors of Optimal Avidity for Tumor AntigensExperimental and theoretical bases for mechanisms of antigen discrimination by T cellsLinking form to function: Biophysical aspects of artificial antigen presenting cell designT cell antigen recognition at the cell membraneTargeting the tumor vasculature to enhance T cell activityA Molecular Basis for the Exquisite CD1d-Restricted Antigen Specificity and Functional Responses of Natural Killer T CellsT Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility ComplexStructural and energetic evidence for highly peptide-specific tumor antigen targeting via allo-MHC restrictionComputational Design of the Affinity and Specificity of a Therapeutic T Cell ReceptorGenetic basis for clinical response to CTLA-4 blockade in melanomaForce measurements of TCR/pMHC recognition at T cell surfaceDistinct influences of peptide-MHC quality and quantity on in vivo T-cell responses.Biophysical mechanism of T-cell receptor triggering in a reconstituted systemAttenuated T cell responses to a high-potency ligand in vivo.Fast on-rates allow short dwell time ligands to activate T cells.Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.Different affinity windows for virus and cancer-specific T-cell receptors: implications for therapeutic strategiesHow the immune system talks to itself: the varied role of synapsesAntigen affinity and antigen dose exert distinct influences on CD4 T-cell differentiationSpyAvidin hubs enable precise and ultrastable orthogonal nanoassembly.Engineering improved T cell receptors using an alanine-scan guided T cell display selection systemImmunomodulatory effects of polysaccharide from marine fungus Phoma herbarum YS4108 on T cells and dendritic cells.Opposite effects of endogenous peptide-MHC class I on T cell activity in the presence and absence of CD8.A detailed mathematical model predicts that serial engagement of IgE-Fc epsilon RI complexes can enhance Syk activation in mast cells.The tumor targeted superantigen ABR-217620 selectively engages TRBV7-9 and exploits TCR-pMHC affinity mimicry in mediating T cell cytotoxicity.Use of TIRF to Monitor T-Lymphocyte Membrane Dynamics with Submicrometer and Subsecond Resolution.Pre-TCR ligand binding impacts thymocyte development before αβTCR expression.Elevated tumor-associated antigen expression suppresses variant peptide vaccine responses.Membrane dynamics shape TCR-generated signaling.Interplay between T cell receptor binding kinetics and the level of cognate peptide presented by major histocompatibility complexes governs CD8+ T cell responsiveness.HLA-DM constrains epitope selection in the human CD4 T cell response to vaccinia virus by favoring the presentation of peptides with longer HLA-DM-mediated half-livesViral antigen density and confinement time regulate the reactivity pattern of CD4 T-cell responses to vaccinia virus infection.Insights from in situ analysis of TCR-pMHC recognition: response of an interaction network.Phenotypic model for early T-cell activation displaying sensitivity, specificity, and antagonism.
P2860
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P2860
Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time.
@ast
Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time.
@en
type
label
Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time.
@ast
Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time.
@en
prefLabel
Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time.
@ast
Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time.
@en
P2093
P2860
P50
P1433
P1476
Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time.
@en
P2093
Eugene Shenderov
Ji-Li Chen
Milos Aleksic
P2860
P304
P356
10.1016/J.IMMUNI.2009.11.013
P407
P577
2010-02-04T00:00:00Z