about
Enduracididine, a rare amino acid component of peptide antibiotics: Natural products and synthesis.Targeting a cell wall biosynthesis hot spot.X-ray crystallographic structure of a teixobactin analogue reveals key interactions of the teixobactin pharmacophore.Alanine scan reveals modifiable residues in teixobactin.Binding Modes of Teixobactin to Lipid II: Molecular Dynamics Study.Are highly morphed peptide frameworks lurking silently in microbial genomes valuable as next generation antibiotic scaffolds?Chemistry and Biology of Teixobactin.Defining the molecular structure of teixobactin analogues and understanding their role in antibacterial activities.Synthesis and biological evaluation of novel teixobactin analogues.Syntheses of potent teixobactin analogues against methicillin-resistant Staphylococcus aureus (MRSA) through the replacement of l-allo-enduracididine with its isosteres.The chemistry and biology of guanidine natural products.Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding.De novo identification of lipid II binding lipopeptides with antibacterial activity against vancomycin-resistant bacteria.Lysine Scanning of Arg-Teixobactin: Deciphering the Role of Hydrophobic and Hydrophilic ResiduesAntibacterial Activity of Teixobactin Derivatives on Clinically Relevant Bacterial Isolates
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 27 May 2016
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Elucidation of the Teixobactin Pharmacophore.
@en
Elucidation of the Teixobactin Pharmacophore.
@nl
type
label
Elucidation of the Teixobactin Pharmacophore.
@en
Elucidation of the Teixobactin Pharmacophore.
@nl
prefLabel
Elucidation of the Teixobactin Pharmacophore.
@en
Elucidation of the Teixobactin Pharmacophore.
@nl
P2093
P2860
P1433
P1476
Elucidation of the Teixobactin Pharmacophore.
@en
P2093
Hyunjun Yang
James S Nowick
Kevin H Chen
P2860
P304
P356
10.1021/ACSCHEMBIO.6B00295
P577
2016-05-27T00:00:00Z