Conditional inactivation of the mouse Wwox tumor suppressor gene recapitulates the null phenotype. - Wikidata - wikimedia - TriplyDB

Conditional inactivation of the mouse Wwox tumor suppressor gene recapitulates the null phenotype.

Conditional inactivation of the mouse Wwox tumor suppressor gene recapitulates the null phenotype.

http://www.wikidata.org/entity/Q37619135

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Tumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage Response Pleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer Cells WW domain-containing oxidoreductase in neuronal injury and neurological diseases.Association of polymorphisms in WWOX gene with risk and outcome of osteosarcoma in a sample of the young Chinese population Alteration of WWOX in human cancer: a clinical view.Role of WW domain proteins WWOX in development, prognosis, and treatment response of glioma.Roles of the WWOX in pathogenesis and endocrine therapy of breast cancer.The common fragile site FRA16D gene product WWOX: roles in tumor suppression and genomic stability.The tumor suppressor WW domain-containing oxidoreductase modulates cell metabolism.Tumor suppressor WWOX regulates glucose metabolism via HIF1α modulation.WWOX-related encephalopathies: delineation of the phenotypical spectrum and emerging genotype-phenotype correlation.Tumor Suppressor WWOX inhibits osteosarcoma metastasis by modulating RUNX2 function.WWOX and p53 Dysregulation Synergize to Drive the Development of Osteosarcoma Correlation between osteosarcoma and the expression of WWOX and p53.The RNA-binding protein, ZC3H14, is required for proper poly(A) tail length control, expression of synaptic proteins, and brain function in mice.WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia.Modeling WWOX Loss of Function : What Have We Learned?Somatic loss of WWOX is associated with TP53 perturbation in basal-like breast cancer

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Conditional inactivation of the mouse Wwox tumor suppressor gene recapitulates the null phenotype.

http://www.wikidata.org/entity/Q37619135

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on July 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Conditional inactivation of th ...... apitulates the null phenotype.

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Conditional inactivation of th ...... apitulates the null phenotype.

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Conditional inactivation of th ...... apitulates the null phenotype.

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Conditional inactivation of th ...... apitulates the null phenotype.

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Conditional inactivation of th ...... apitulates the null phenotype.

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Conditional inactivation of th ...... apitulates the null phenotype.

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Journal of Cellular Physiology

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Conditional inactivation of th ...... apitulates the null phenotype.

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Gary S Stein

http://www.w3.org/2001/XMLSchema#string

Jane B Lian

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Janet L Stein

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John Hagan

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Maysoon Rawahneh

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Muhannad Abu-Remaileh

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Rami I Aqeilan

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Sadeeq Hussain

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Sara Del Mare

http://www.w3.org/2001/XMLSchema#string

Stacey Russell

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WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer

Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells

WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function

WWOX: a candidate tumor suppressor gene involved in multiple tumor types

Functional association between Wwox tumor suppressor protein and p73, a p53 homolog

Targeted deletion of Wwox reveals a tumor suppressor function

Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies

Loss of WWOX expression in gastric carcinoma

The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism

Generation and characterization of mice carrying a conditional allele of the Wwox tumor suppressor gene

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1377-1382

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scholarly article

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10.1002/JCP.24308

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7

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228

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2013-07-01T00:00:00Z

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23254685

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