In vivo protein-DNA interactions at the beta-globin gene locus.
about
Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeastIsolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control regionThe ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogeneInteraction of NF-E2 in the human beta-globin locus control region before chromatin remodelinghMAF, a small human transcription factor that heterodimerizes specifically with Nrf1 and Nrf2Nrf2 is essential for protection against acute pulmonary injury in miceNRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and developmentA negative cis-element regulates the level of enhancement by hypersensitive site 2 of the beta-globin locus control region.Fine tuning of globin gene expression by DNA methylation.In vivo protein-DNA interactions at hypersensitive site 3 of the human beta-globin locus control region.The role of trans-acting factors and DNA-bending in the silencing of human beta-globin gene expression.A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblastsGATA-1 binding sites mapped in the beta-globin locus by using mammalian chIp-chip analysis.Synthetic human beta-globin 5'HS2 constructs function as locus control regions only in multicopy transgene concatamers.Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene.Mechanism for fetal globin gene expression: role of the soluble guanylate cyclase-cGMP-dependent protein kinase pathway.Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific chromatin domain.Multiple elements in human beta-globin locus control region 5' HS 2 are involved in enhancer activity and position-independent, transgene expressionCharacterization of the factors binding to a PEPCK gene upstream hypersensitive site with LCR activity.The proinflammatory cytokine GM-CSF downregulates fetal hemoglobin expression by attenuating the cAMP-dependent pathway in sickle cell disease.GATA transcription factors associate with a novel class of nuclear bodies in erythroblasts and megakaryocytes.Structure and function of the murine beta-globin locus control region 5' HS-3.Rhabdomyosarcoma arising in transgenic mice harboring the beta-globin locus control region fused with simian virus 40 large T antigen gene.Transcription of the HS2 enhancer toward a cis-linked gene is independent of the orientation, position, and distance of the enhancer relative to the gene.Enhancer-dependent transcription of the epsilon-globin promoter requires promoter-bound GATA-1 and enhancer-bound AP-1/NF-E2Transcriptional activation of human zeta 2 globin promoter by the alpha globin regulatory element (HS-40): functional role of specific nuclear factor-DNA complexes.Activity and expression of murine small Maf family protein MafK.Germ-line transmission and developmental regulation of a 150-kb yeast artificial chromosome containing the human beta-globin locus in transgenic miceA 36-base-pair core sequence of locus control region enhances retrovirally transferred human beta-globin gene expression.Functional erythroid promoters created by interaction of the transcription factor GATA-1 with CACCC and AP-1/NFE-2 elements.Dissection of the enhancer activity of beta-globin 5' DNase I-hypersensitive site 2 in transgenic mice.Signalling pathways involved in paracetamol-induced hepatotoxicity: new insights on the role of protein tyrosine phosphatase 1B.The erythroid Krüppel-like factor transactivation domain is a critical component for cell-specific inducibility of a beta-globin promoter.In vivo protein-DNA interactions at the c-jun promoter: preformed complexes mediate the UV response.Globin gene switching. In vivo protein-DNA interactions of the human beta-globin locus in erythroid cells expressing the fetal or the adult globin gene program.CACCC and GATA-1 sequences make the constitutively expressed alpha-globin gene erythroid-responsive in mouse erythroleukemia cells.Protein-DNA interactions in the human beta-globin locus control region hypersensitive site-2 as revealed by four nitrogen mustards.Comparative analysis of the locus control region of the rabbit beta-like gene cluster: HS3 increases transient expression of an embryonic epsilon-globin gene.Exploring strategies for the design of artificial transcription factors: targeting sites proximal to known regulatory regions for the induction of gamma-globin expression and the treatment of sickle cell disease.Transcriptional up-regulation of the mouse cytosolic glutathione peroxidase gene in erythroid cells is due to a tissue-specific 3' enhancer containing functionally important CACC/GT motifs and binding sites for GATA and Ets transcription factors.
P2860
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P2860
In vivo protein-DNA interactions at the beta-globin gene locus.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh
1991年學術文章
@zh-hant
name
In vivo protein-DNA interactions at the beta-globin gene locus.
@en
In vivo protein-DNA interactions at the beta-globin gene locus.
@nl
type
label
In vivo protein-DNA interactions at the beta-globin gene locus.
@en
In vivo protein-DNA interactions at the beta-globin gene locus.
@nl
prefLabel
In vivo protein-DNA interactions at the beta-globin gene locus.
@en
In vivo protein-DNA interactions at the beta-globin gene locus.
@nl
P2860
P356
P1476
In vivo protein-DNA interactions at the beta-globin gene locus.
@en
P2860
P304
10188-10192
P356
10.1073/PNAS.88.22.10188
P407
P577
1991-11-01T00:00:00Z