RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.
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UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activityEpigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical ImplicationsEpigenetic regulation of hematopoietic stem cell agingHistone demethylase lysine demethylase 5B in development and cancerPotent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.The role of GATA2 in lethal prostate cancer aggressiveness.Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2.Epigenetic Control of Stem Cell Potential during Homeostasis, Aging, and DiseaseThe H3K4-Methyl Epigenome Regulates Leukemia Stem Cell Oncogenic Potential.Transcriptional Regulation of JARID1B/KDM5B Histone Demethylase by Ikaros, Histone Deacetylase 1 (HDAC1), and Casein Kinase 2 (CK2) in B-cell Acute Lymphoblastic Leukemia.The roles of Jumonji-type oxygenases in human disease.JARID1B Enables Transit between Distinct States of the Stem-like Cell Population in Oral CancersProfiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing.Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2.The histone demethylase Jarid1b is required for hematopoietic stem cell self-renewal in mice.Forward RNAi Screens in Human Hematopoietic Stem Cells.Runt-Related Transcription Factor 2 Induction During Differentiation of Wharton's Jelly Mesenchymal Stem Cells to Osteoblasts Is Regulated by Jumonji AT-Rich Interactive Domain 1B Histone Demethylase.JARID1 Histone Demethylases: Emerging Targets in Cancer.The chromatin-associated Sin3B protein is required for hematopoietic stem cell functions in mice.Targeting JARID1B's demethylase activity blocks a subset of its functions in oral cancer.
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RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 June 2013
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vetenskaplig artikel
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RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.
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RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.
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RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.
@en
RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.
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RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.
@en
RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.
@nl
P2093
P2860
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RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.
@en
P2093
Alexander Thompson
Brian T Wilhelm
Guy Sauvageau
Jalila Chagraoui
Jana Krosl
Josette R Landry
Keith Humphries
Kristin J Hope
Martin Sauvageau
Nadine Mayotte
P2860
P304
P356
10.1182/BLOOD-2013-04-496281
P407
P577
2013-06-18T00:00:00Z