STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line.
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The role of STAT3 in granulocyte colony-stimulating factor-induced enhancement of neutrophilic differentiation of Me2SO-treated HL-60 cells. GM-CSF inhibits the nuclear translocation of tyrosine-phosphorylated STAT3Thrombin inhibits tumor cell growth in association with up-regulation of p21(waf/cip1) and caspases via a p53-independent, STAT-1-dependent pathwayRequirement of STAT3 activation for differentiation of mucosal stratified squamous epithelium.A point mutation in the N-terminal coiled-coil domain releases c-Fes tyrosine kinase activity and survival signaling in myeloid leukemia cellsDifferential binding to and regulation of JAK2 by the SH2 domain and N-terminal region of SH2-bbetaSelf-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3Targeted disruption of the mouse Stat3 gene leads to early embryonic lethalitySignal transducers and activators of transcription as regulators of growth, apoptosis and breast development.Influence of subunit combinations on signaling by receptors for oncostatin M, leukemia inhibitory factor, and interleukin-6Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathyLIF-dependent signaling: new pieces in the LegoTranscriptional activation of the suppressor of cytokine signaling-3 (SOCS-3) gene via STAT3 is increased in F9 REX1 (ZFP-42) knockout teratocarcinoma stem cells relative to wild-type cellsProteomic analysis of apoptosis initiation induced by all-trans retinoic acid in human acute promyelocytic leukemia cells.Three LIF-dependent signatures and gene clusters with atypical expression profiles, identified by transcriptome studies in mouse ES cells and early derivativesA single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas.Regulation of signal transducer and activator of transcription 3 enhanceosome formation by apurinic/apyrimidinic endonuclease 1 in hepatic acute phase response.The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo.Stat3 activation is required for cellular transformation by v-src.Signaling through Gp130: toward a general scenario of cytokine action.IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathwaysThe adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6.The role of STATs in transcriptional control and their impact on cellular function.The role of STATs in myeloid differentiation and leukemia.Roles of STAT3 defined by tissue-specific gene targeting.Control of myeloid differentiation and survival by Stats.Regulation of Id gene expression by type I insulin-like growth factor: roles of Stat3 and the tyrosine 950 residue of the receptor.Distinct role of gp130 activation in promoting self-renewal divisions by mitogenically stimulated murine hematopoietic stem cells.Activation of STAT proteins and growth control.CCAAT/Enhancer Binding Protein-delta (C/EBP-delta) regulates cell growth, migration and differentiationNuclear localization of signal transducer and activator of transcription 3 in head and neck squamous cell carcinoma is associated with a better prognosisThe paradigm of IL-6: from basic science to medicineMonoclonal Antibodies Specific for STAT3β Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer.Essential role of STAT3 for embryonic stem cell pluripotencySuppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3.Endoplasmic reticulum stress inhibits STAT3-dependent suppression of hepatic gluconeogenesis via dephosphorylation and deacetylation.Cross-talk between retinoic acid and STAT3 signaling pathways in acute promyelocytic leukemia.Tyrosine-599 of the c-Mpl receptor is required for Shc phosphorylation and the induction of cellular differentiationClassic interleukin-6 receptor signaling and interleukin-6 trans-signaling differentially control angiotensin II-dependent hypertension, cardiac signal transducer and activator of transcription-3 activation, and vascular hypertrophy in vivo.Activation of the Jak3 pathway and myeloid differentiation.
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STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
STAT3 activation is a critical ...... arrest of a myeloid cell line.
@en
STAT3 activation is a critical ...... arrest of a myeloid cell line.
@nl
type
label
STAT3 activation is a critical ...... arrest of a myeloid cell line.
@en
STAT3 activation is a critical ...... arrest of a myeloid cell line.
@nl
prefLabel
STAT3 activation is a critical ...... arrest of a myeloid cell line.
@en
STAT3 activation is a critical ...... arrest of a myeloid cell line.
@nl
P2093
P2860
P356
P1476
STAT3 activation is a critical ...... arrest of a myeloid cell line.
@en
P2093
Kishimoto T
Matsumoto M
P2860
P304
P356
10.1073/PNAS.93.9.3963
P407
P577
1996-04-01T00:00:00Z