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Epigenetic alterations in agingCellular Senescence as the Causal Nexus of AgingNuclear lamins and oxidative stress in cell proliferation and longevityHeading in the Right Direction: Understanding Cellular Orientation Responses to Complex Biophysical EnvironmentsA dual role for A-type lamins in DNA double-strand break repairProgeria syndromes and ageing: what is the connection?Nuclear lamins.Lentiviral expression of anti-microRNAs targeting miR-27a inhibits proliferation and invasiveness of U87 glioma cells.DNA repair defects and genome instability in Hutchinson-Gilford Progeria Syndrome.Methods to Monitor DNA Repair Defects and Genomic Instability in the Context of a Disrupted Nuclear Lamina.Purkinje cell degeneration in pcd mice reveals large scale chromatin reorganization and gene silencing linked to defective DNA repair'Relax and Repair' to restrain aging.Aging genetics and aging.Oxidative stress induces an ATM-independent senescence pathway through p38 MAPK-mediated lamin B1 accumulation.Lamins at a glance.Nuclear mechanics in cancerBRCA1 loss activates cathepsin L-mediated degradation of 53BP1 in breast cancer cells.Exposure to chemical cocktails before or after conception--- the effect of timing on ovarian development.Novel roles of 1α,25(OH)2D3 on DNA repair provide new strategies for breast cancer treatmentNurturing the genome: A-type lamins preserve genomic stability.Regulating the levels of key factors in cell cycle and DNA repair: new pathways revealed by lamins.Biological implications and regulatory mechanisms of long-range chromosomal interactions.Progeria, rapamycin and normal aging: recent breakthrough.Mammalian telomeres and their partnership with lamins.Mechanosensing by the nucleus: From pathways to scaling relationships.Lamin A Δexon9 mutation leads to telomere and chromatin defects but not genomic instability.Differences in 53BP1 and BRCA1 regulation between cycling and non-cycling cells.The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence.A Lamin-Binding Ligand Inhibits Homologous Recombination Repair of DNA Double-Strand BreaksAntioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 15 December 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Loss of A-type lamins and genomic instability.
@en
Loss of A-type lamins and genomic instability.
@nl
type
label
Loss of A-type lamins and genomic instability.
@en
Loss of A-type lamins and genomic instability.
@nl
prefLabel
Loss of A-type lamins and genomic instability.
@en
Loss of A-type lamins and genomic instability.
@nl
P2093
P356
P1433
P1476
Loss of A-type lamins and genomic instability.
@en
P2093
Abena B Redwood
Ignacio Gonzalez-Suarez
Susana Gonzalo
P304
P356
10.4161/CC.8.23.10092
P577
2009-12-15T00:00:00Z