The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival.
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C1D family proteins in coordinating RNA processing, chromosome condensation and DNA damage responsePosttranscriptional Regulation of Splicing Factor SRSF1 and Its Role in Cancer Cell BiologyMolecular modeling and docking of small molecule inhibitors against NEK2Abnormal expression of Nek2 in pancreatic ductal adenocarcinoma: a novel marker for prognosisNek2 is a novel regulator of B cell development and immunological response.Role of NEK2A in human cancer and its therapeutic potentials.New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicingOverexpression of NIMA-related kinase 2 is associated with progression and poor prognosis of prostate cancer.Silencing of E2F3 suppresses tumor growth of Her2+ breast cancer cells by restricting mitosisTargeting NEK2 as a promising therapeutic approach for cancer treatment.NEK2 serves as a prognostic biomarker for hepatocellular carcinoma.Structural investigations of the RNA-binding properties of STAR proteins.Hepatoma cell functions modulated by NEK2 are associated with liver cancer progression.Effect of silencing NEK2 on biological behaviors of HepG2 in human hepatoma cells and MAPK signal pathway.An Overview on Predictive Biomarkers of Testicular Germ Cell Tumors.High levels of GPR30 protein in human testicular carcinoma in situ and seminomas correlate with low levels of estrogen receptor-beta and indicate a switch in estrogen responsiveness.Regulation of BCL-X splicing reveals a role for the polypyrimidine tract binding protein (PTBP1/hnRNP I) in alternative 5' splice site selection.Alternative splicing and cell survival: from tissue homeostasis to disease.NEK2 Promotes Aerobic Glycolysis in Multiple Myeloma Through Regulating Splicing of Pyruvate Kinase.EMT and stemness: flexible processes tuned by alternative splicing in development and cancer progression.Overexpression of the Nek2 kinase in colorectal cancer correlates with beta-catenin relocalization and shortened cancer-specific survival.Highly preserved consensus gene modules in human papilloma virus 16 positive cervical cancer and head and neck cancers.hnRNP A1/A2 and Sam68 collaborate with SRSF10 to control the alternative splicing response to oxaliplatin-mediated DNA damage.The Krebs Cycle Connection: Reciprocal Influence Between Alternative Splicing Programs and Cell Metabolism
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The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival.
@en
The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival.
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type
label
The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival.
@en
The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival.
@nl
prefLabel
The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival.
@en
The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival.
@nl
P2860
P50
P356
P1476
The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival.
@en
P2860
P304
P356
10.1093/NAR/GKT1307
P407
P577
2013-12-24T00:00:00Z