Allelic variation in the effects of the nef gene on replication of human immunodeficiency virus type 1. - Wikidata - wikimedia - TriplyDB

Allelic variation in the effects of the nef gene on replication of human immunodeficiency virus type 1.

Allelic variation in the effects of the nef gene on replication of human immunodeficiency virus type 1.

http://www.wikidata.org/entity/Q37639095

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Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4 Binding of c-Raf1 kinase to a conserved acidic sequence within the carboxyl-terminal region of the HIV-1 Nef protein Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complex Pathogenesis of human immunodeficiency virus infection Disulfide bond formation in the human immunodeficiency virus type 1 Nef protein HIV-1 Nef-mediated T-cell activation and chemotaxis are decoupled using a HIV-1/SIVpbj1.9. chimeric nef variant.Physical and functional interaction of Nef with Lck. HIV-1 Nef-induced T-cell signaling defects.Human immunodeficiency virus type 1 nef quasispecies in pathological tissue The nef gene of simian immunodeficiency virus SIVmac1A11 OrfA downregulates feline immunodeficiency virus primary receptor CD134 on the host cell surface and is important in viral infection.Positive and negative aspects of the human immunodeficiency virus protease: development of inhibitors versus its role in AIDS pathogenesis Nef stimulates human immunodeficiency virus type 1 replication in primary T cells by enhancing virion-associated gp120 levels: coreceptor-dependent requirement for Nef in viral replication.Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes.Mechanism of action of regulatory proteins encoded by complex retroviruses Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis vif-negative human immunodeficiency virus type 1 persistently replicates in primary macrophages, producing attenuated progeny virus.The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages.Severe immunodeficiency associated with a human immunodeficiency virus 1 NEF/3'-long terminal repeat transgene CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type 1-infected individuals.Dual role of autophagy in HIV-1 replication and pathogenesis Upstream U3 sequences in simian immunodeficiency virus are selectively deleted in vivo in the absence of an intact nef gene.Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene.Molecular biology of the human immunodeficiency virus accessory proteins The human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection.A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex.Mutational analysis of the human immunodeficiency virus type 1 Eli Nef function.Human immunodeficiency virus type 1 Nef protein targets CD4 to the multivesicular body pathway.The activity of Nef on HIV-1 infectivity Regulation of human immunodeficiency virus type 1 infectivity by the ERK mitogen-activated protein kinase signaling pathway.Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry.Deletion of nef slows but does not prevent CD4-positive T-cell depletion in human immunodeficiency virus type 1-infected human-PBL-SCID mice.Human immunodeficiency virus type 1 Nef protein down-regulates transcription factors NF-kappa B and AP-1 in human T cells in vitro after T-cell receptor stimulation.Primary human immunodeficiency virus type 1 nef alleles show major differences in pathogenicity in transgenic mice.Viral gene products and replication of the human immunodeficiency type 1 virus.The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes.

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Allelic variation in the effects of the nef gene on replication of human immunodeficiency virus type 1.

http://www.wikidata.org/entity/Q37639095

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on December 1991

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Allelic variation in the effec ...... immunodeficiency virus type 1.

@en

Allelic variation in the effec ...... immunodeficiency virus type 1.

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type

label

Allelic variation in the effec ...... immunodeficiency virus type 1.

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Allelic variation in the effec ...... immunodeficiency virus type 1.

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prefLabel

Allelic variation in the effec ...... immunodeficiency virus type 1.

@en

Allelic variation in the effec ...... immunodeficiency virus type 1.

@nl

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PNAS.88.23.10971

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Proceedings of the National Academy of Sciences of the United States of America

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Allelic variation in the effec ...... immunodeficiency virus type 1.

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D Gabuzda

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E F Terwilliger

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E Langhoff

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E Zazopoulos

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P2860

Complete nucleotide sequence of the AIDS virus, HTLV-III

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

The role of mononuclear phagocytes in HTLV-III/LAV infection

Human immunodeficiency virus type 1 negative factor is a transcriptional silencer.

Effects of mutations within the 3' orf open reading frame region of human T-cell lymphotropic virus type III (HTLV-III/LAV) on replication and cytopathogenicity

Identification of HIV-1 vpr product and function.

Structure of simian immunodeficiency virus regulatory genes

Functional role of human immunodeficiency virus type 1 vpu.

Isolates of human immunodeficiency virus type 1 from the brain may constitute a special group of the AIDS virus.

Lack of a negative influence on viral growth by the nef gene of human immunodeficiency virus type 1.

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10971-10975

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scholarly article

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10.1073/PNAS.88.23.10971

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23

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88

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William A. Haseltine

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1991-12-01T00:00:00Z

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21434342

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1720558

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53054

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