A 3D structural model and dynamics of hepatitis C virus NS3/4A protease (genotype 4a, strain ED43) suggest conformational instability of the catalytic triad: implications in catalysis and drug resistivity.
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Comparative molecular dynamics simulation of Hepatitis C Virus NS3/4A protease (Genotypes 1b, 3a and 4b) predicts conformational instability of the catalytic triad in drug resistant strainsThe NS4A Cofactor Dependent Enhancement of HCV NS3 Protease Activity Correlates with a 4D Geometrical Measure of the Catalytic Triad Region.Hepatitis C Virus Genotype 1 to 6 Protease Inhibitor Escape Variants: In Vitro Selection, Fitness, and Resistance Patterns in the Context of the Infectious Viral Life Cycle.Over-expression and characterization of NS3 and NS5A of Hepatitis C virus genotype 3a.
P2860
A 3D structural model and dynamics of hepatitis C virus NS3/4A protease (genotype 4a, strain ED43) suggest conformational instability of the catalytic triad: implications in catalysis and drug resistivity.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 14 June 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A 3D structural model and dyna ...... atalysis and drug resistivity.
@en
A 3D structural model and dyna ...... atalysis and drug resistivity.
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type
label
A 3D structural model and dyna ...... atalysis and drug resistivity.
@en
A 3D structural model and dyna ...... atalysis and drug resistivity.
@nl
prefLabel
A 3D structural model and dyna ...... atalysis and drug resistivity.
@en
A 3D structural model and dyna ...... atalysis and drug resistivity.
@nl
P2093
P2860
P1476
A 3D structural model and dyna ...... atalysis and drug resistivity.
@en
P2093
Bradley Rimmert
Edward Ackad
Mohammad S Yousef
Salwa Sabet
P2860
P304
P356
10.1080/07391102.2013.800001
P577
2013-06-14T00:00:00Z