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Functional Characterization and Drug Response of Freshly Established Patient-Derived Tumor Models with CpG Island Methylator PhenotypeMicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mTOR and IGF-1R.From genotype to functional phenotype: unraveling the metabolomic features of colorectal cancer.Establishment and characterization of cell lines from chromosomal instable colorectal cancer.NDRG4, a novel candidate tumor suppressor, is a predictor of overall survival of colorectal cancer patients.Chorein addiction in VPS13A overexpressing rhabdomyosarcoma cellsPro-survival responses to the dual inhibition of anti-apoptotic Bcl-2 family proteins and mTOR-mediated signaling in hypoxic colorectal carcinoma cellsPterostilbine, an active component of blueberries, sensitizes colon cancer cells to 5-fluorouracil cytotoxicity.Diacylglycerol kinase-ζ regulates mTORC1 and lipogenic metabolism in cancer cells through SREBP-1Combination of cetuximab and PP242 synergistically suppress the progression of wild-type KRAS colorectal carcinoma.Halofuginone inhibits colorectal cancer growth through suppression of Akt/mTORC1 signaling and glucose metabolism.miRNA-99b-5p suppresses liver metastasis of colorectal cancer by down-regulating mTORRapamycin and WYE-354 suppress human gallbladder cancer xenografts in micemTOR disruption causes intestinal epithelial cell defects and intestinal atrophy postinjury in mice.Mesenchymal stem cells promote colorectal cancer progression through AMPK/mTOR-mediated NF-κB activation.N-Hydroxyphthalimide exhibits antitumor activity by suppressing mTOR signaling pathway in BT-20 and LoVo cells.Lactobacilli Differentially Modulate mTOR and Wnt/ β-Catenin Pathways in Different Cancer Cell Lines.Icariside II, a natural mTOR inhibitor, disrupts aberrant energy homeostasis via suppressing mTORC1-4E-BP1 axis in sarcoma cellsTRIM44 promotes proliferation and metastasis in non‑small cell lung cancer via mTOR signaling pathway.Translationally controlled tumour protein TCTP is induced early in human colorectal tumours and contributes to the resistance of HCT116 colon cancer cells to 5-FU and oxaliplatin.Personalized medicine in hematology - A landmark from bench to bedIntegrin αvβ6 sets the stage for colorectal cancer metastasis.Role of CSL-dependent and independent Notch signaling pathways in cell apoptosis.Therapeutic potential of mTOR inhibitors for targeting cancer stem cells.mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer.Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation.Long non-coding RNA-CRNDE: a novel regulator of tumor growth and angiogenesis in hepatoblastomaCancer: Linking Powerhouses to Suicidal Bags.The zinc sensing receptor, ZnR/GPR39, controls proliferation and differentiation of colonocytes and thereby tight junction formation in the colon.Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem Cells.Hypothesis: cell signalling influences age-related risk of colorectal cancer.Targeting PP2A activates AMPK signaling to inhibit colorectal cancer cells.CD177+ neutrophils suppress epithelial cell tumourigenesis in colitis-associated cancer and predict good prognosis in colorectal cancer.Evaluation of the Effect of Everolimus on Retinal Pigment Epithelial Cells and Experimental Proliferative Vitreoretinopathy.Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations.Invitro Evaluation of Torin2 and 2, 6-Dihydroxyacetophenone in Colorectal Cancer Therapy.Loss of fatty acid synthase suppresses the malignant phenotype of colorectal cancer cells by down-regulating energy metabolism and mTOR signaling pathway.MicroRNA-99b promotes -induced autophagyand suppresses carcinogenesis by targeting mTOR
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
mTOR pathway in colorectal cancer: an update.
@en
mTOR pathway in colorectal cancer: an update.
@nl
type
label
mTOR pathway in colorectal cancer: an update.
@en
mTOR pathway in colorectal cancer: an update.
@nl
prefLabel
mTOR pathway in colorectal cancer: an update.
@en
mTOR pathway in colorectal cancer: an update.
@nl
P2860
P921
P356
P1433
P1476
mTOR pathway in colorectal cancer: an update.
@en
P2093
Eric Lagasse
P2860
P356
10.18632/ONCOTARGET.1548
P407
P5008
P577
2014-01-01T00:00:00Z
2014-01-15T00:00:00Z