Rel-deficient T cells exhibit defects in production of interleukin 3 and granulocyte-macrophage colony-stimulating factor - Wikidata - wikimedia - TriplyDB

Rel-deficient T cells exhibit defects in production of interleukin 3 and granulocyte-macrophage colony-stimulating factor

Rel-deficient T cells exhibit defects in production of interleukin 3 and granulocyte-macrophage colony-stimulating factor

http://www.wikidata.org/entity/Q37654865

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Notch1 augments NF-kappaB activity by facilitating its nuclear retention GM-CSF promoter chromatin remodelling and gene transcription display distinct signal and transcription factor requirements A key role for NF-κB transcription factor c-Rel in T-lymphocyte-differentiation and effector functions The c-Rel transcription factor and B-cell proliferation: a deal with the devil NF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses Bhlhe40 controls cytokine production by T cells and is essential for pathogenicity in autoimmune neuroinflammation.The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockouts.The combined absence of NF-kappa B1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells.Genetic evidence for Shc requirement in TCR-induced c-Rel nuclear translocation and IL-2 expression.The PTK-STAT signaling pathway has essential roles in T-cell activation in response to antigen stimulation.Deficiency of C-C chemokine receptor 5 suppresses tumor development via inactivation of NF-κB and upregulation of IL-1Ra in melanoma model The clinical implication and molecular mechanism of preferential IL-4 production by modified glycolipid-stimulated NKT cells.Depletion of c-Rel from cytokine gene promoters is required for chromatin reassembly and termination of gene responses to T cell activation.NF-kappaB family of transcription factors: central regulators of innate and adaptive immune functions.Regulation of the interleukin-2 CD28-responsive element by NF-ATp and various NF-kappaB/Rel transcription factors.Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation Kinetic perspectives of T cell antigen receptor signaling. A two-tier model for T cell full activation.Spaceflight and simulated microgravity cause a significant reduction of key gene expression in early T-cell activation NF-κB and BRG1 bind a distal regulatory element in the IL-3/GM-CSF locus Requirement for NF-kappaB in osteoclast and B-cell development Loss of c-REL but not NF-κB2 prevents autoimmune disease driven by FasL mutation.Distinct mechanisms of immunosuppression as a consequence of major surgery Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages.The Rel subunit of NF-kappaB-like transcription factors is a positive and negative regulator of macrophage gene expression: distinct roles for Rel in different macrophage populations Signaling pathways in Th2 development.Rel induces interferon regulatory factor 4 (IRF-4) expression in lymphocytes: modulation of interferon-regulated gene expression by rel/nuclear factor kappaB.c-Rel regulates interleukin 12 p70 expression in CD8(+) dendritic cells by specifically inducing p35 gene transcription.Shaping alternative NF-kappaB-dependent gene expression programs: new clues to specificity.B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells.The Rel/NF-κB pathway and transcription of immediate early genes in T cell activation are inhibited by microgravity.Tuning up inflammation: how DNA sequence and chromatin organization control the induction of inflammatory genes by NF-kappaB.The transcription factors c-rel and RelA control epidermal development and homeostasis in embryonic and adult skin via distinct mechanisms.Antitumor activity of IL-32β through the activation of lymphocytes, and the inactivation of NF-κB and STAT3 signals Sam68 modulates the promoter specificity of NF-κB and mediates expression of CD25 in activated T cells.Aging-dependent upregulation of IL-23p19 gene expression in dendritic cells is associated with differential transcription factor binding and histone modifications.Distinct roles for the NF-kappaB1 (p50) and c-Rel transcription factors in inflammatory arthritis.Deoxyribonucleic acid triplex formation inhibits granulocyte macrophage colony-stimulating factor gene expression and suppresses growth in juvenile myelomonocytic leukemic cells Regulation of an essential innate immune response by the p50 subunit of NF-kappaB.Transcriptional control of the TNF gene

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Rel-deficient T cells exhibit defects in production of interleukin 3 and granulocyte-macrophage colony-stimulating factor

http://www.wikidata.org/entity/Q37654865

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on April 1996

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Rel-deficient T cells exhibit ...... hage colony-stimulating factor

@en

Rel-deficient T cells exhibit ...... age colony-stimulating factor.

@nl

type

label

Rel-deficient T cells exhibit ...... hage colony-stimulating factor

@en

Rel-deficient T cells exhibit ...... age colony-stimulating factor.

@nl

prefLabel

Rel-deficient T cells exhibit ...... hage colony-stimulating factor

@en

Rel-deficient T cells exhibit ...... age colony-stimulating factor.

@nl

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Proceedings of the National Academy of Sciences of the United States of America

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Rel-deficient T cells exhibit ...... hage colony-stimulating factor

@en

P2093

Gerondakis S

http://www.w3.org/2001/XMLSchema#string

Grigoriadis G

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Grumont RJ

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Metcalf D

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P2860

Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation

Cyclic AMP-independent ATF family members interact with NF-kappa B and function in the activation of the E-selectin promoter in response to cytokines

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

The inducible transcription activator NF-kappa B: regulation by distinct protein subunits

Kappa B-specific DNA binding proteins: role in the regulation of human interleukin-2 gene expression

Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-kappa B

Function and activation of NF-kappa B in the immune system

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

Structure, regulation and function of NF-kappa B

Leukemic transformation of immortalized FDC-P1 cells engrafted in GM-CSF transgenic mice.

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3405-3409

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10.1073/PNAS.93.8.3405

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8

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93

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Jean-Pierre Y Scheerlinck

Andreas Strasser

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1996-04-01T00:00:00Z

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14577509

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8622948

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39621

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