Comparative cardiac gene delivery of adeno-associated virus serotypes 1-9 reveals that AAV6 mediates the most efficient transduction in mouse heart.
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Gene therapy for cardiovascular disease: advances in vector development, targeting, and delivery for clinical translationThe potential of sarcospan in adhesion complex replacement therapeutics for the treatment of muscular dystrophyGRK2 in the heart: a GPCR kinase and beyondRegulation of in vivo cardiac contractility by phospholemman: role of Na+/Ca2+ exchange.Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skippingComparative analysis of adeno-associated virus capsid stability and dynamicsCell-type specific oxytocin gene expression from AAV delivered promoter deletion constructs into the rat supraoptic nucleus in vivo.Gene replacement therapies for duchenne muscular dystrophy using adeno-associated viral vectors.Adeno-associated viral (AAV) vectors do not efficiently target muscle satellite cellsTherapeutic approaches to muscular dystrophy.Gene therapy for neurologic manifestations of mucopolysaccharidoses.Intranasal administration of adeno-associated virus type 12 (AAV12) leads to transduction of the nasal epithelia and can initiate transgene-specific immune responseNeutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal modelsIntracellular transport of recombinant adeno-associated virus vectors.A pharmacokinetic analysis of molecular cardiac surgery with recirculation mediated delivery of βARKct gene therapy: developing a quantitative definition of the therapeutic window.Myocardial β(2) -adrenoceptor gene delivery promotes coordinated cardiac adaptive remodelling and angiogenesis in heart failure.Blockade of β-adrenoceptors restores the GRK2-mediated adrenal α(2) -adrenoceptor-catecholamine production axis in heart failureDevelopment of optimized AAV3 serotype vectors: mechanism of high-efficiency transduction of human liver cancer cellsComparison of adeno-associated virus serotypes and delivery methods for cardiac gene transfer.AAV6-βARKct gene delivery mediated by molecular cardiac surgery with recirculating delivery (MCARD) in sheep results in robust gene expression and increased adrenergic reserve.Determination of Anti-Adeno-Associated Viral Vector Neutralizing Antibodies in Patients With Heart Failure in the Cardiovascular Foundation of Colombia (ANVIAS): Study Protocol.Targeted modifications in adeno-associated virus serotype 8 capsid improves its hepatic gene transfer efficiency in vivoAn emerging adeno-associated viral vector pipeline for cardiac gene therapyNeuro-hormonal effects of physical activity in the elderly.Heparin-binding correlates with increased efficiency of AAV1- and AAV6-mediated transduction of striated muscle, but negatively impacts CNS transductionGRK2 as a novel gene therapy target in heart failure.Regenerative therapies in electrophysiology and pacing: introducing the next steps.Adrenal adrenoceptors in heart failure.β1-adrenergic receptor and sphingosine-1-phosphate receptor 1 (S1PR1) reciprocal downregulation influences cardiac hypertrophic response and progression to heart failure: protective role of S1PR1 cardiac gene therapyCharacterization of the Adeno-Associated Virus 1 and 6 Sialic Acid Binding SiteCardiac gene therapy: are we there yet?Promise of adeno-associated virus as a gene therapy vector for cardiovascular diseases.Recombinant Adeno-Associated Virus Serotype 6 (rAAV6) Potently and Preferentially Transduces Rat Astrocytes In vitro and In vivo.Spacial and Temporal Patterns of Gene Expression After Cardiac MEK1 Gene Transfer Improve Post-Infarction Remodeling Without Inducing Global Hypertrophy.Improved adeno-associated virus (AAV) serotype 1 and 5 vectors for gene therapy.Adeno-associated virus serotype 1 (AAV1)- and AAV5-antibody complex structures reveal evolutionary commonalities in parvovirus antigenic reactivity.Minimally invasive closed-chest ultrasound-guided substance delivery into the pericardial space in miceC-reactive protein (CRP) is essential for efficient systemic transduction of recombinant adeno-associated virus vector 1 (rAAV-1) and rAAV-6 in mice.Ex vivo intracoronary gene transfer of adeno-associated virus 2 leads to superior transduction over serotypes 8 and 9 in rat heart transplants.Gene transfer of heme oxygenase-1 using an adeno-associated virus serotype 6 vector prolongs cardiac allograft survival.
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Comparative cardiac gene delivery of adeno-associated virus serotypes 1-9 reveals that AAV6 mediates the most efficient transduction in mouse heart.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on June 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Comparative cardiac gene deliv ...... t transduction in mouse heart.
@en
Comparative cardiac gene deliv ...... t transduction in mouse heart.
@nl
type
label
Comparative cardiac gene deliv ...... t transduction in mouse heart.
@en
Comparative cardiac gene deliv ...... t transduction in mouse heart.
@nl
prefLabel
Comparative cardiac gene deliv ...... t transduction in mouse heart.
@en
Comparative cardiac gene deliv ...... t transduction in mouse heart.
@nl
P2093
P2860
P1476
Comparative cardiac gene deliv ...... t transduction in mouse heart.
@en
P2093
Joseph E Rabinowitz
Stephen Soltys
Walter J Koch
P2860
P356
10.1111/J.1752-8062.2010.00190.X
P407
P577
2010-06-01T00:00:00Z