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Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas

Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas

http://www.wikidata.org/entity/Q37658327

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Action mechanisms of histone deacetylase inhibitors in the treatment of hematological malignancies Structural Mechanisms and Drug Discovery Prospects of Rho GTPases Functions of TET Proteins in Hematopoietic Transformation Is lineage decision-making restricted during tumoral reprograming of haematopoietic stem cells?The double face of Morgana in tumorigenesis G17V RHOA: Genetic evidence of GTP-unbound RHOA playing a role in tumorigenesis in T cells Connections between TET proteins and aberrant DNA modification in cancer Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond IDH2R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma.The RhoA-ROCK pathway in the regulation of T and B cell responses Role of TET enzymes in DNA methylation, development, and cancer Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression Comprehensive molecular characterization of gastric adenocarcinoma Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma Romidepsin in peripheral and cutaneous T-cell lymphoma: mechanistic implications from clinical and correlative data Data on affected cancer-related genes in pediatric t(12;21)-positive acute lymphoblastic leukemia patients harboring unbalanced der(6)t(X;6) translocations.Angioimmunoblastic T cell lymphoma: novel molecular insights by mutation profiling.Toward a Biology-Driven Treatment Strategy for Peripheral T-cell Lymphoma Molecular Testing of Lymphoproliferative Disorders: Current Status and Perspectives.The curious origins of angioimmunoblastic T-cell lymphoma Detection of the G17V RHOA mutation in angioimmunoblastic T-cell lymphoma and related lymphomas using quantitative allele-specific PCR.Global transcriptome analysis and enhancer landscape of human primary T follicular helper and T effector lymphocytes.DNMT3A in haematological malignancies.The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome TET proteins and the control of cytosine demethylation in cancer.Gentamicin arrests cancer cell growth: the intriguing involvement of nuclear sphingomyelin metabolism Loss of RhoA Exacerbates, Rather Than Dampens, Oncogenic K-Ras Induced Lung Adenoma Formation in Mice.Distinct Viral and Mutational Spectrum of Endemic Burkitt Lymphoma.Concurrent Mutations in ATM and Genes Associated with Common γ Chain Signaling in Peripheral T Cell Lymphoma.TET proteins and 5-methylcytosine oxidation in hematological cancers STX11 functions as a novel tumor suppressor gene in peripheral T-cell lymphomas Identification of cell-type-specific mutations in nodal T-cell lymphomas.Molecular basis of targeted therapy in T/NK-cell lymphoma/leukemia: A comprehensive genomic and immunohistochemical analysis of a panel of 33 cell lines DNA methylation and hydroxymethylation in hematologic differentiation and transformation.Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents.Redundant and nonredundant roles for Cdc42 and Rac1 in lymphomas developed in NPM-ALK transgenic mice.The Impact of DNA Methylation in Hematopoietic Malignancies.CD1d-restricted peripheral T cell lymphoma in mice and humans.A novel patient-derived tumorgraft model with TRAF1-ALK anaplastic large-cell lymphoma translocation.DNMT3A(R882H) mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice

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Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas

http://www.wikidata.org/entity/Q37658327

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 12 January 2014

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

Recurrent mutations in epigene ...... in peripheral T cell lymphomas

@en

Recurrent mutations in epigene ...... n peripheral T cell lymphomas.

@nl

type

label

Recurrent mutations in epigene ...... in peripheral T cell lymphomas

@en

Recurrent mutations in epigene ...... n peripheral T cell lymphomas.

@nl

prefLabel

Recurrent mutations in epigene ...... in peripheral T cell lymphomas

@en

Recurrent mutations in epigene ...... n peripheral T cell lymphomas.

@nl

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Nature Genetics

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Recurrent mutations in epigene ...... in peripheral T cell lymphomas

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Adolfo A Ferrando

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Arianne Perez-Garcia

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Christian Bastard

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Concha Nicolas

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Francesco Abate

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Izidore S Lossos

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J Erika Haydu

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Maddalena Allegretta

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Mi-Yeon Kim

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Milagros Balbin

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The binding protein for globular heads of complement C1q, gC1qR. Functional expression and characterization as a novel vitronectin binding factor

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

I-TASSER: a unified platform for automated protein structure and function prediction

Signaling networks of Rho GTPases in cell motility

Structure of a constitutively activated RhoA mutant (Q63L) at 1.55 A resolution

IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma.

UCSF Chimera--a visualization system for exploratory research and analysis

Fast gapped-read alignment with Bowtie 2

Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells

Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain

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166-170

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scholarly article

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10.1038/NG.2873

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2

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Miguel A. Piris

Lucile Couronné

Hossein Khiabanian

Alberto Ambesi-Impiombato

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2014-01-12T00:00:00Z

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259699441

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1040376253

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24413734

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