Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells
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Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs)MAGI-3 regulates LPA-induced activation of Erk and RhoAThe GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunitsRho family Guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling systemAutomated NMR fragment based screening identified a novel interface blocker to the LARG/RhoA complexThe A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophyHigh-throughput screening for small-molecule inhibitors of LARG-stimulated RhoA nucleotide binding via a novel fluorescence polarization assayStructure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors.The Lbc Rho guanine nucleotide exchange factor α-catulin axis functions in serotonin-induced vascular smooth muscle cell mitogenesis and RhoA/ROCK activation.Distribution of endogenous farnesyl pyrophosphate and four species of lysophosphatidic acid in rodent brain.Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury.Distinctive G Protein-Dependent Signaling by Protease-Activated Receptor 2 (PAR2) in Smooth Muscle: Feedback Inhibition of RhoA by cAMP-Independent PKA.Omega-3 fatty acids and other FFA4 agonists inhibit growth factor signaling in human prostate cancer cells.Determinants at the N- and C-termini of Gα12 required for activation of Rho-mediated signaling.Regulation of focal adhesion kinase activation, breast cancer cell motility, and amoeboid invasion by the RhoA guanine nucleotide exchange factor Net1.PDZ-RhoGEF is essential for CXCR4-driven breast tumor cell motility through spatial regulation of RhoA.Unc5B associates with LARG to mediate the action of repulsive guidance molecule.A conserved hydrophobic surface of the LARG pleckstrin homology domain is critical for RhoA activation in cells.Breast cancer migration and invasion depend on proteasome degradation of regulator of G-protein signaling 4.Regulation and physiological functions of G12/13-mediated signaling pathways.Regulation of RhoGEF proteins by G12/13-coupled receptors.ROCK mediates phorbol ester-induced apoptosis in prostate cancer cells via p21Cip1 up-regulation and JNK.Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomasG12/13-dependent signaling of G-protein-coupled receptors: disease context and impact on drug discovery.I'm coming to GEF you: Regulation of RhoGEFs during cell migration.Dynamics of Gαq-protein-p63RhoGEF interaction and its regulation by RGS2.RhoA/mDia-1/profilin-1 signaling targets microvascular endothelial dysfunction in diabetic retinopathy.Sphingosine 1-phosphate receptor 2 signals through leukemia-associated RhoGEF (LARG), to promote smooth muscle cell differentiation.Neuropeptide-stimulated cell migration in prostate cancer cells is mediated by RhoA kinase signaling and inhibited by neutral endopeptidase.Mitotic-dependent phosphorylation of leukemia-associated RhoGEF (LARG) by Cdk1.Lysophosphatidic acid prevents apoptosis of Caco-2 colon cancer cells via activation of mitogen-activated protein kinase and phosphorylation of Bad.Gα13/PDZ-RhoGEF/RhoA signaling is essential for gastrin-releasing peptide receptor-mediated colon cancer cell migration.A role for Gab1/SHP2 in thrombin activation of PAK1: gene transfer of kinase-dead PAK1 inhibits injury-induced restenosis.Curcumin inhibits LPA-induced invasion by attenuating RhoA/ROCK/MMPs pathway in MCF7 breast cancer cells.
P2860
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P2860
Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Thrombin and lysophosphatidic ...... oGEFs in prostate cancer cells
@ast
Thrombin and lysophosphatidic ...... oGEFs in prostate cancer cells
@en
Thrombin and lysophosphatidic ...... oGEFs in prostate cancer cells
@nl
type
label
Thrombin and lysophosphatidic ...... oGEFs in prostate cancer cells
@ast
Thrombin and lysophosphatidic ...... oGEFs in prostate cancer cells
@en
Thrombin and lysophosphatidic ...... oGEFs in prostate cancer cells
@nl
prefLabel
Thrombin and lysophosphatidic ...... oGEFs in prostate cancer cells
@ast
Thrombin and lysophosphatidic ...... oGEFs in prostate cancer cells
@en
Thrombin and lysophosphatidic ...... oGEFs in prostate cancer cells
@nl
P2093
P2860
P356
P1476
Thrombin and lysophosphatidic ...... oGEFs in prostate cancer cells
@en
P2093
Jeffrey D Rothstein
Paul C Sternweis
Tohru Kozasa
P2860
P304
28831-28834
P356
10.1074/JBC.C400105200
P407
P50
P577
2004-05-13T00:00:00Z