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Regulation of protein homeostasis in neurodegenerative diseases: the role of coding and non-coding genesProtein folding and quality control in the ERBiP and its nucleotide exchange factors Grp170 and Sil1: mechanisms of action and biological functionsMolecular chaperones in targeting misfolded proteins for ubiquitin-dependent degradationThe Crystal Structure of the Human Co-Chaperone P58IPKDaedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectorsClose and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiPInvolvement of dopamine receptors in binge methamphetamine-induced activation of endoplasmic reticulum and mitochondrial stress pathwaysERdj4 protein is a soluble endoplasmic reticulum (ER) DnaJ family protein that interacts with ER-associated degradation machineryHeat shock protein responses to aging and proteotoxicity in the olfactory bulb.The BiP molecular chaperone plays multiple roles during the biogenesis of torsinA, an AAA+ ATPase associated with the neurological disease early-onset torsion dystonia.The endoplasmic reticulum protein folding factory and its chaperones: new targets for drug discovery?Chaperoning G protein-coupled receptors: from cell biology to therapeuticsSalicylic acid signaling controls the maturation and localization of the arabidopsis defense protein ACCELERATED CELL DEATH6Dissection of structural and functional requirements that underlie the interaction of ERdj3 protein with substrates in the endoplasmic reticulum.Diverse pathways for maturation of the Na,K-ATPase β1 and β2 subunits in the endoplasmic reticulum of Madin-Darby canine kidney cellsRole of human sec63 in modulating the steady-state levels of multi-spanning membrane proteins.Sil1, a nucleotide exchange factor for BiP, is not required for antibody assembly or secretionRoles of endoplasmic reticulum stress and unfolded protein response associated genes in seed stratification and bud endodormancy during chilling accumulation in Prunus persicaProinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes.The nucleotide exchange factors Grp170 and Sil1 induce cholera toxin release from BiP to enable retrotranslocation.Sec63 and Xbp1 regulate IRE1α activity and polycystic disease severity.Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes.Activity-induced synaptic delivery of the GluN2A-containing NMDA receptor is dependent on endoplasmic reticulum chaperone Bip and involved in fear memoryC-terminal mutations destabilize SIL1/BAP and can cause Marinesco-Sjögren syndrome.ADP ribosylation adapts an ER chaperone response to short-term fluctuations in unfolded protein load.Endoplasmic reticulum stress sensing in the unfolded protein responseERdj3 regulates BiP occupancy in living cells.How early studies on secreted and membrane protein quality control gave rise to the ER associated degradation (ERAD) pathway: the early history of ERAD.Two phases of disulfide bond formation have differing requirements for oxygen.SAHA enhances Proteostasis of epilepsy-associated α1(A322D)β2γ2 GABA(A) receptors.Links between ER stress and autophagy in plantsThe large Hsp70 Grp170 binds to unfolded protein substrates in vivo with a regulation distinct from conventional Hsp70s.Deficiency of the BiP cochaperone ERdj4 causes constitutive endoplasmic reticulum stress and metabolic defectsGlycoprotein folding and quality-control mechanisms in protein-folding diseasesThe multi-faceted nature of HLA class I dimer molecules.Protein folding in the endoplasmic reticulumThe safety dance: biophysics of membrane protein folding and misfolding in a cellular contextOrganelle autoregulation-stress responses in the ER, Golgi, mitochondria and lysosome.GRP78 at the Centre of the Stage in Cancer and Neuroprotection.
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 21 December 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Life and death of a BiP substrate
@en
Life and death of a BiP substrate.
@nl
type
label
Life and death of a BiP substrate
@en
Life and death of a BiP substrate.
@nl
prefLabel
Life and death of a BiP substrate
@en
Life and death of a BiP substrate.
@nl
P2093
P2860
P1476
Life and death of a BiP substrate
@en
P2093
Beáta Lizák
Joel H Otero
Linda M Hendershot
P2860
P304
P356
10.1016/J.SEMCDB.2009.12.008
P577
2009-12-21T00:00:00Z