Mammalian target of rapamycin promotes oligodendrocyte differentiation, initiation and extent of CNS myelination.
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Remyelination Therapy in Multiple SclerosisThe neurology of mTOROligodendrocyte precursor cell-intrinsic effect of Rheb1 controls differentiation and mediates mTORC1-dependent myelination in brainHeterogeneity in oligodendroglia: Is it relevant to mouse models and human disease?Cyclin-dependent kinase 5 mediates adult OPC maturation and myelin repair through modulation of Akt and GsK-3β signaling.Role of ERK1/2 MAPK signaling in the maintenance of myelin and axonal integrity in the adult CNS.Phosphorylation of LKB1/Par-4 establishes Schwann cell polarity to initiate and control myelin extentThe thrombin receptor is a critical extracellular switch controlling myelination.Interaction of mTOR and Erk1/2 signaling to regulate oligodendrocyte differentiation.Translational control of myelin basic protein expression by ERK2 MAP kinase regulates timely remyelination in the adult brainOlig1 function is required for oligodendrocyte differentiation in the mouse brain.Myelin Proteolipid Protein Complexes with αv Integrin and AMPA Receptors In Vivo and Regulates AMPA-Dependent Oligodendrocyte Progenitor Cell Migration through the Modulation of Cell-Surface GluR2 Expression.Altered Oligodendrocyte Maturation and Myelin Maintenance: The Role of Antiretrovirals in HIV-Associated Neurocognitive Disorders.Fbxw7 Limits Myelination by Inhibiting mTOR Signaling.Co-ultramicronized Palmitoylethanolamide/Luteolin Promotes the Maturation of Oligodendrocyte Precursor CellsImpairment of Oligodendroglia Maturation Leads to Aberrantly Increased Cortical Glutamate and Anxiety-Like Behaviors in Juvenile MiceHypomyelination following deletion of Tsc2 in oligodendrocyte precursors.Clemastine Enhances Myelination in the Prefrontal Cortex and Rescues Behavioral Changes in Socially Isolated Mice.Interplay between exercise and dietary fat modulates myelinogenesis in the central nervous system.Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytesCholesterol Biosynthesis Supports Myelin Gene Expression and Axon Ensheathment through Modulation of P13K/Akt/mTor Signaling.ERK1/2 Activation in Preexisting Oligodendrocytes of Adult Mice Drives New Myelin Synthesis and Enhanced CNS Function.Conditional ablation of raptor or rictor has differential impact on oligodendrocyte differentiation and CNS myelination.Function and Mechanisms of Autophagy in Brain and Spinal Cord Trauma.mTOR in Brain Physiology and Pathologies.Intracellular signaling pathway regulation of myelination and remyelination in the CNS.The cell biology of CNS myelination.Signaling by FGF Receptor 2, Not FGF Receptor 1, Regulates Myelin Thickness through Activation of ERK1/2-MAPK, Which Promotes mTORC1 Activity in an Akt-Independent Manner.A Neuron-Specific Gene Therapy Relieves Motor Deficits in Pompe Disease Mice.Perspective: The Potential Role of Essential Amino Acids and the Mechanistic Target of Rapamycin Complex 1 (mTORC1) Pathway in the Pathogenesis of Child Stunting.Modification of autophagy-lysosomal pathway as a neuroprotective treatment for spinal cord injuryDual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system.Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex.S1P1 deletion in oligodendroglial lineage cells: Effect on differentiation and myelination.Developmental changes in plasticity, synaptic, glia and connectivity protein levels in rat dorsal hippocampus.Loss of mTORC2 signaling in oligodendrocyte precursor cells delays myelination.mTOR regulates peripheral nerve response to tensile strain.Anti-inflammatory effects of hypoxia-preconditioned human periodontal ligament cell secretome in an experimental model of multiple sclerosis: a key role of IL-37.Targeted Knockdown of Bone Morphogenetic Protein Signaling within Neural Progenitors Protects the Brain and Improves Motor Function following Postnatal Hypoxia-Ischemia.Co-Ultramicronized Palmitoylethanolamide/Luteolin Facilitates the Development of Differentiating and Undifferentiated Rat Oligodendrocyte Progenitor Cells.
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Mammalian target of rapamycin promotes oligodendrocyte differentiation, initiation and extent of CNS myelination.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on March 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Mammalian target of rapamycin ...... and extent of CNS myelination.
@en
Mammalian target of rapamycin ...... and extent of CNS myelination.
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type
label
Mammalian target of rapamycin ...... and extent of CNS myelination.
@en
Mammalian target of rapamycin ...... and extent of CNS myelination.
@nl
prefLabel
Mammalian target of rapamycin ...... and extent of CNS myelination.
@en
Mammalian target of rapamycin ...... and extent of CNS myelination.
@nl
P2093
P2860
P1476
Mammalian target of rapamycin ...... and extent of CNS myelination
@en
P2093
Kathryn K Bercury
Lauren E McLane
Wendy B Macklin
P2860
P304
P356
10.1523/JNEUROSCI.4311-13.2014
P407
P577
2014-03-01T00:00:00Z