Conditional ablation of raptor or rictor has differential impact on oligodendrocyte differentiation and CNS myelination.
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Mammalian Target of Rapamycin: Its Role in Early Neural Development and in Adult and Aged Brain FunctionRemyelination Therapy in Multiple SclerosisThe neurology of mTOROligodendrocyte precursor cell-intrinsic effect of Rheb1 controls differentiation and mediates mTORC1-dependent myelination in brainTricornered Kinase Regulates Synapse Development by Regulating the Levels of Wiskott-Aldrich Syndrome ProteinHeterogeneity in oligodendroglia: Is it relevant to mouse models and human disease?Role of ERK1/2 MAPK signaling in the maintenance of myelin and axonal integrity in the adult CNS.Phosphorylation of LKB1/Par-4 establishes Schwann cell polarity to initiate and control myelin extentInteraction of mTOR and Erk1/2 signaling to regulate oligodendrocyte differentiation.Translational control of myelin basic protein expression by ERK2 MAP kinase regulates timely remyelination in the adult brainOlig1 function is required for oligodendrocyte differentiation in the mouse brain.Myelin Proteolipid Protein Complexes with αv Integrin and AMPA Receptors In Vivo and Regulates AMPA-Dependent Oligodendrocyte Progenitor Cell Migration through the Modulation of Cell-Surface GluR2 Expression.Fbxw7 Limits Myelination by Inhibiting mTOR Signaling.Hypomyelination following deletion of Tsc2 in oligodendrocyte precursors.The scales and tales of myelination: using zebrafish and mouse to study myelinating gliaRegulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytesCholesterol Biosynthesis Supports Myelin Gene Expression and Axon Ensheathment through Modulation of P13K/Akt/mTor Signaling.ERK1/2 Activation in Preexisting Oligodendrocytes of Adult Mice Drives New Myelin Synthesis and Enhanced CNS Function.Mammalian target of rapamycin promotes oligodendrocyte differentiation, initiation and extent of CNS myelination.Functional organization of an Mbp enhancer exposes striking transcriptional regulatory diversity within myelinating glia.Schwann cell myelinationmTOR in Brain Physiology and Pathologies.Intracellular signaling pathway regulation of myelination and remyelination in the CNS.The cell biology of CNS myelination.Signaling by FGF Receptor 2, Not FGF Receptor 1, Regulates Myelin Thickness through Activation of ERK1/2-MAPK, Which Promotes mTORC1 Activity in an Akt-Independent Manner.Rapidly Progressive White Matter Involvement in Early Childhood: The Expanding Phenotype of Infantile Onset Pompe?Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy.Identification of expression quantitative trait loci of RPTOR for susceptibility to glioma.Modification of autophagy-lysosomal pathway as a neuroprotective treatment for spinal cord injuryDual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system.A new model of cuprizone-mediated demyelination/remyelination.Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex.Loss of mTORC2 signaling in oligodendrocyte precursor cells delays myelination.Bad wrap: Myelin and myelin plasticity in health and disease.Loss of Tuberous Sclerosis Complex1 in Adult Oligodendrocyte Progenitor Cells Enhances Axon Remyelination and Increases Myelin Thickness after a Focal Demyelination.Myelination and mTOR.PTEN negatively regulates the cell lineage progression from NG2+ glial progenitor to oligodendrocyte via mTOR-independent signaling.Multiple lines of inhibitory feedback on AKT kinase in Schwann cells lacking TSC1/2 hint at distinct functions of mTORC1 and AKT in nerve development.mTORC1 is transiently reactivated in injured nerves to promote c-Jun elevation and Schwann cell dedifferentiation.The TSC1-mTOR-PLK axis regulates the homeostatic switch from Schwann cell proliferation to myelination in a stage-specific manner.
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Conditional ablation of raptor or rictor has differential impact on oligodendrocyte differentiation and CNS myelination.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Conditional ablation of raptor ...... entiation and CNS myelination.
@en
Conditional ablation of raptor ...... entiation and CNS myelination.
@nl
type
label
Conditional ablation of raptor ...... entiation and CNS myelination.
@en
Conditional ablation of raptor ...... entiation and CNS myelination.
@nl
prefLabel
Conditional ablation of raptor ...... entiation and CNS myelination.
@en
Conditional ablation of raptor ...... entiation and CNS myelination.
@nl
P2093
P2860
P1476
Conditional ablation of raptor ...... rentiation and CNS myelination
@en
P2093
Hilary H Sachs
JinXiang Dai
Kathryn K Bercury
Wendy B Macklin
P2860
P304
P356
10.1523/JNEUROSCI.4314-13.2014
P407
P577
2014-03-01T00:00:00Z