Notch signaling specifies megakaryocyte development from hematopoietic stem cells.
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The aryl hydrocarbon receptor (AHR) transcription factor regulates megakaryocytic polyploidizationEndoreplication: polyploidy with purposePlatelet generation in vivo and in vitroGenomic landscape of megakaryopoiesis and platelet function defectsEndoreplication and polyploidy: insights into development and diseaseHematopoietic stem cell niche maintenance during homeostasis and regenerationThe evolving role of the aryl hydrocarbon receptor (AHR) in the normophysiology of hematopoiesisThree-Dimensional Environment Sustains Hematopoietic Stem Cell Differentiation into Platelet-Producing MegakaryocytesThe OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model.Infusion of megakaryocytic progenitor products generated from cord blood hematopoietic stem/progenitor cells: results of the phase 1 study.Arachidonic acid and Docosahexanoic acid enhance platelet formation from human apheresis-derived CD34+ cells.O-fucose modulates Notch-controlled blood lineage commitment.Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies.Notch1 intracellular domain increases cytoplasmic EZH2 levels during early megakaryopoiesis.Reactive oxygen species in normal and tumor stem cells.Assessment of human multi-potent hematopoietic stem/progenitor cell potential using a single in vitro screening system.Cytosolic carboxypeptidase CCP6 is required for megakaryopoiesis by modulating Mad2 polyglutamylationCombination of HOXB4 and Delta-1 ligand improves expansion of cord blood cellsNotch2 governs the rate of generation of mouse long- and short-term repopulating stem cellsA novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.Constitutive Notch pathway activation in murine ZMYM2-FGFR1-induced T-cell lymphomas associated with atypical myeloproliferative disease.Crosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specificationMegakaryocytes differentially sort mRNAs for matrix metalloproteinases and their inhibitors into platelets: a mechanism for regulating synthetic events.An overview of notch signaling in adult tissue renewal and maintenance.The homeobox gene DLX4 regulates erythro-megakaryocytic differentiation by stimulating IL-1β and NF-κB signalingNotch Stimulates Both Self-Renewal and Lineage Plasticity in a Subset of Murine CD9High Committed Megakaryocytic Progenitors.The regulation of normal and leukemic hematopoietic stem cells by niches.Notch pathway activation targets AML-initiating cell homeostasis and differentiation.Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signalingFunctional regulation of FoxO1 in neural stem cell differentiationNOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia.Signal integration and crosstalk during thymocyte migration and emigrationNotch signaling in acute promyelocytic leukemiaCommon features of megakaryocytes and hematopoietic stem cells: what's the connection?In vivo mapping of notch pathway activity in normal and stress hematopoiesis.Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitorsNotch signaling in the hematopoietic system.Hematopoietic stem cell injury induced by ionizing radiation.Notch1-promoted TRPA1 expression in erythroleukemic cells suppresses erythroid but enhances megakaryocyte differentiation.Hyperexpression of NOTCH-1 is found in immature acute myeloid leukemia.
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Notch signaling specifies megakaryocyte development from hematopoietic stem cells.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on September 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Notch signaling specifies megakaryocyte development from hematopoietic stem cells.
@en
Notch signaling specifies megakaryocyte development from hematopoietic stem cells.
@nl
type
label
Notch signaling specifies megakaryocyte development from hematopoietic stem cells.
@en
Notch signaling specifies megakaryocyte development from hematopoietic stem cells.
@nl
prefLabel
Notch signaling specifies megakaryocyte development from hematopoietic stem cells.
@en
Notch signaling specifies megakaryocyte development from hematopoietic stem cells.
@nl
P2093
P2860
P1433
P1476
Notch signaling specifies megakaryocyte development from hematopoietic stem cells
@en
P2093
Christopher Sears
D Gary Gilliland
Jon C Aster
Melanie G Cornejo
Sandra A Moore
Thomas Kindler
Warren S Pear
P2860
P304
P356
10.1016/J.STEM.2008.07.010
P407
P577
2008-09-01T00:00:00Z