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Novel lipid signaling pathways in Alzheimer's disease pathogenesis.

Novel lipid signaling pathways in Alzheimer's disease pathogenesis.

http://www.wikidata.org/entity/Q37678676

about

A spiked tissue-based approach for quantification of phosphatidylcholines in brain section by MALDI mass spectrometry imaging.Regulation of gamma-secretase activating protein by the 5Lipoxygenase: in vitro and in vivo evidence PRECISION MEDICINE - The Golden Gate for Detection, Treatment and Prevention of Alzheimer's Disease.Five lipoxygenase hypomethylation mediates the homocysteine effect on Alzheimer's phenotype.Function of Nogo-A/Nogo-A receptor in Alzheimer's disease.Molecular Mechanisms of Vascular Dementia: What Can Be Learned from Animal Models of Chronic Cerebral Hypoperfusion?Pharmacologic blockade of 12/15-lipoxygenase ameliorates memory deficits, Aβ and tau neuropathology in the triple-transgenic mice.Overexpression of 5-Lipoxygenase Worsens the Phenotype of a Mouse Model of Tauopathy.Evolving Relevance of Neuroproteomics in Alzheimer's Disease.5-LOX in Alzheimer's Disease: Potential Serum Marker and In Vitro Evidences for Rescue of Neurotoxicity by Its Inhibitor YWCS.Antileukotriene therapy by reducing tau phosphorylation improves synaptic integrity and cognition of P301S transgenic mice.Novel Key Players in the Development of Tau Neuropathology: Focus on the 5-Lipoxygenase.Early Life Stress and Epigenetics in Late-onset Alzheimer's Dementia: A Systematic Review

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Novel lipid signaling pathways in Alzheimer's disease pathogenesis.

http://www.wikidata.org/entity/Q37678676

description

2013 nî lūn-bûn

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2013年の論文

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2013年学术文章

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2013年学术文章

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2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

2013年學術文章

@zh

2013年學術文章

@zh-hant

name

Novel lipid signaling pathways in Alzheimer's disease pathogenesis.

@en

Novel lipid signaling pathways in Alzheimer's disease pathogenesis.

@nl

type

label

Novel lipid signaling pathways in Alzheimer's disease pathogenesis.

@en

Novel lipid signaling pathways in Alzheimer's disease pathogenesis.

@nl

prefLabel

Novel lipid signaling pathways in Alzheimer's disease pathogenesis.

@en

Novel lipid signaling pathways in Alzheimer's disease pathogenesis.

@nl

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Q37678676-C8D6A43B-9B17-4085-AC8F-AAC11EB5BB60

P356

J.BCP.2013.11.005

P1433

Biochemical Pharmacology

P1476

Novel lipid signaling pathways in Alzheimer's disease pathogenesis.

@en

P2093

Domenico Praticò

http://www.w3.org/2001/XMLSchema#string

Phillip F Giannopoulos

http://www.w3.org/2001/XMLSchema#string

Yash B Joshi

http://www.w3.org/2001/XMLSchema#string

P2860

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

Gene knockout of 5-lipoxygenase rescues synaptic dysfunction and improves memory in the triple-transgenic model of Alzheimer's disease.

5-lipoxygenase as an endogenous modulator of amyloid β formation in vivo.

Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin, Aph-1, and Pen-2.

Pharmacologic blockade of 5-lipoxygenase improves the amyloidotic phenotype of an Alzheimer's disease transgenic mouse model involvement of γ-secretase

Zileuton improves memory deficits, amyloid and tau pathology in a mouse model of Alzheimer's disease with plaques and tangles.

Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice.

5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of Alzheimer disease.

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560-564

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scholarly article

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10.1016/J.BCP.2013.11.005

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4

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2013-11-21T00:00:00Z

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24269629

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Alzheimer's disease

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3972350

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