DYNC1H1 mutations associated with neurological diseases compromise processivity of dynein-dynactin-cargo adaptor complexes. - Wikidata - wikimedia - TriplyDB

DYNC1H1 mutations associated with neurological diseases compromise processivity of dynein-dynactin-cargo adaptor complexes.

DYNC1H1 mutations associated with neurological diseases compromise processivity of dynein-dynactin-cargo adaptor complexes.

http://www.wikidata.org/entity/Q37682387

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Phenotypic extremes of BICD2-opathies: from lethal, congenital muscular atrophy with arthrogryposis to asymptomatic with subclinical features.Differential effects of the dynein-regulatory factor Lissencephaly-1 on processive dynein-dynactin motility.Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated Lissencephaly-1 is a context-dependent regulator of the human dynein complex.Disease-associated mutations in human BICD2 hyperactivate motility of dynein-dynactin.A novel mouse model carrying a human cytoplasmic dynein mutation shows motor behavior deficits consistent with Charcot-Marie-Tooth type 2O disease.Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility.A mathematical understanding of how cytoplasmic dynein walks on microtubules

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DYNC1H1 mutations associated with neurological diseases compromise processivity of dynein-dynactin-cargo adaptor complexes.

http://www.wikidata.org/entity/Q37682387

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 14 February 2017

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

DYNC1H1 mutations associated w ...... actin-cargo adaptor complexes.

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DYNC1H1 mutations associated w ...... actin-cargo adaptor complexes.

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DYNC1H1 mutations associated w ...... actin-cargo adaptor complexes.

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DYNC1H1 mutations associated w ...... actin-cargo adaptor complexes.

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DYNC1H1 mutations associated w ...... actin-cargo adaptor complexes.

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DYNC1H1 mutations associated w ...... actin-cargo adaptor complexes.

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PNAS.1620141114

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Proceedings of the National Academy of Sciences of the United States of America

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DYNC1H1 mutations associated w ...... actin-cargo adaptor complexes.

@en

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Ha Thi Hoang

http://www.w3.org/2001/XMLSchema#string

Max A Schlager

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P2860

Exome sequencing identifies a DYNC1H1 mutation in a large pedigree with dominant axonal Charcot-Marie-Tooth disease

Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex

Molecular defects in the motor adaptor BICD2 cause proximal spinal muscular atrophy with autosomal-dominant inheritance

Review: Structure and mechanism of the dynein motor ATPase

Cdk1 Activates Pre-mitotic Nuclear Envelope Dynein Recruitment and Apical Nuclear Migration in Neural Stem Cells

Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry

Structural Basis for Microtubule Binding and Release by Dynein

The 2.8 Å crystal structure of the dynein motor domain

In vitro reconstitution of a highly processive recombinant human dynein complex

Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes.

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E1597-E1606

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scholarly article

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10.1073/PNAS.1620141114

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9

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Simon L. Bullock

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2017-02-14T00:00:00Z

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