A dominant role for CD8+-T-lymphocyte selection in simian immunodeficiency virus sequence variation.
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Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) responseThe hope for an HIV vaccine based on induction of CD8+ T lymphocytes--a reviewThe evolutionary biology of poxvirusesHepatitis C virus adaptation to T-cell immune pressureSIV genome-wide pyrosequencing provides a comprehensive and unbiased view of variation within and outside CD8 T lymphocyte epitopesViral CTL escape mutants are generated in lymph nodes and subsequently become fixed in plasma and rectal mucosa during acute SIV infection of macaquesViral Sequence Evolution in Acute Hepatitis C Virus InfectionMore effective purifying selection on RNA viruses than in DNA virusesHLA-driven convergence of HIV-1 viral subtypes B and F toward the adaptation to immune responses in human populationsCD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation.Two MHC class I molecules associated with elite control of immunodeficiency virus replication, Mamu-B*08 and HLA-B*2705, bind peptides with sequence similarity.Frequent associations between CTL and T-Helper epitopes in HIV-1 genomes and implications for multi-epitope vaccine designsCodon-based tests of positive selection, branch lengths, and the evolution of mammalian immune system genes.Dynamics of haplotype frequency change in a CD8+TL epitope of simian immunodeficiency virus.Constrained pattern of viral evolution in acute and early HCV infection limits viral plasticity.MHC heterozygote advantage in simian immunodeficiency virus-infected Mauritian cynomolgus macaques.The role of recombination for the coevolutionary dynamics of HIV and the immune responseHuman immunodeficiency virus mutations during the first month of infection are preferentially found in known cytotoxic T-lymphocyte epitopes.The role of MHC class I allele Mamu-A*07 during SIV(mac)239 infectionNef-specific CD45RA+ CD8+ T cells secreting MIP-1beta but not IFN-gamma are associated with nonprogressive HIV-1 infection.Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolutionA structural constraint for functional interaction between N-terminal and C-terminal domains in simian immunodeficiency virus capsid proteins.Sequence evolution of HIV-1 following mother-to-child transmission.Fluidity of HIV-1-specific T-cell responses during acute and early subtype C HIV-1 infection and associations with early disease progression.Involvement of multiple epitope-specific cytotoxic T-lymphocyte responses in vaccine-based control of simian immunodeficiency virus replication in rhesus macaques.Acute phase CD8+ T lymphocytes against alternate reading frame epitopes select for rapid viral escape during SIV infectionTranscriptionally abundant major histocompatibility complex class I alleles are fundamental to nonhuman primate simian immunodeficiency virus-specific CD8+ T cell responses.HIV-1 Subtype C Phylodynamics in the Global EpidemicTransmission of clonal hepatitis C virus genomes reveals the dominant but transitory role of CD8⁺ T cells in early viral evolution.CD8+ T cell escape mutations in simian immunodeficiency virus SIVmac239 cause fitness defects in vivo, and many revert after transmissionPyrosequencing reveals restricted patterns of CD8+ T cell escape-associated compensatory mutations in simian immunodeficiency virus.Rapid reversion of sequence polymorphisms dominates early human immunodeficiency virus type 1 evolution.Simian immunodeficiency virus SIVmac239 infection of major histocompatibility complex-identical cynomolgus macaques from Mauritius.CTL Escape and Viral Fitness in HIV/SIV InfectionThe antiviral efficacy of simian immunodeficiency virus-specific CD8+ T cells is unrelated to epitope specificity and is abrogated by viral escape.Subdominant CD8+ T-cell responses are involved in durable control of AIDS virus replication.Noncytolytic CD8+ Cell Mediated Antiviral Response Represents a Strong Element in the Immune Response of Simian Immunodeficiency Virus-Infected Long-Term Non-Progressing Rhesus Macaques.Experimental analysis of sources of error in evolutionary studies based on Roche/454 pyrosequencing of viral genomes.AIDS virus specific CD8+ T lymphocytes against an immunodominant cryptic epitope select for viral escapeA Novel Codon-optimized SIV Gag-pol Immunogen for Gene-based Vaccination
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A dominant role for CD8+-T-lymphocyte selection in simian immunodeficiency virus sequence variation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2004
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A dominant role for CD8+-T-lym ...... ency virus sequence variation.
@en
A dominant role for CD8+-T-lym ...... ency virus sequence variation.
@nl
type
label
A dominant role for CD8+-T-lym ...... ency virus sequence variation.
@en
A dominant role for CD8+-T-lym ...... ency virus sequence variation.
@nl
prefLabel
A dominant role for CD8+-T-lym ...... ency virus sequence variation.
@en
A dominant role for CD8+-T-lym ...... ency virus sequence variation.
@nl
P2093
P2860
P50
P1433
P1476
A dominant role for CD8+-T-lym ...... ency virus sequence variation.
@en
P2093
Adrian B McDermott
Austin L Hughes
Dennis R Burton
Edna J Gonzalez
Elizabeth J Dodds
Helen Piontkivska
Jacqueline E Miller
Kendall C Krebs
Nancy Wilson
Ralph Pantophlet
P2860
P304
14012-14022
P356
10.1128/JVI.78.24.14012-14022.2004
P407
P577
2004-12-01T00:00:00Z