The metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cells.
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Autophagy in malignant transformation and cancer progressionIn Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I MetabolitesSignaling and stress: The redox landscape in NOS2 biologyThe anticancer agent di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes prosurvival autophagy by two mechanisms: persistent induction of autophagosome synthesis and impairment of lysosomal integrity.Smyd1 facilitates heart development by antagonizing oxidative and ER stress responses.The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1.Potentiating the cellular targeting and anti-tumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cells.Cell intrinsic and extrinsic activators of the unfolded protein response in cancer: Mechanisms and targets for therapyTargeting cancer by binding iron: Dissecting cellular signaling pathwaysThe Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling PathwaysThe iron chelator Dp44mT suppresses osteosarcoma's proliferation, invasion and migration: in vitro and in vivoGene of the month: BECN1.Deconvoluting the relationships between autophagy and metastasis for potential cancer therapy.Targeting metastasis.Targeting autophagy in antitumor agent design: furthering the 'lysosomal love' strategy.Copper and conquer: copper complexes of di-2-pyridylketone thiosemicarbazones as novel anti-cancer therapeutics.Autophagy and epithelial-mesenchymal transition: an intricate interplay in cancer.Autophagy as an Emerging Common Pathomechanism in Inherited Peripheral Neuropathies.Knockdown of NDRG1 promote epithelial-mesenchymal transition of colorectal cancer via NF-κB signaling.Ndrg1 promotes adipocyte differentiation and sustains their function.Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart.NDRG1 inhibition sensitizes osteosarcoma cells to combretastatin A-4 through targeting autophagy.Laparoscopic surgery inhibits the proliferation and metastasis of cervical cancer cellsIRON METABOLISM AND AUTOPHAGY: A POORLY EXPLORED RELATIONSHIP THAT HAS IMPORTANT CONSEQUENCES FOR HEALTH AND DISEASE.N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly.Lipid accumulation in human breast cancer cells injured by iron depletors.Global Proteomic Changes Induced by the Epstein-Barr Virus Oncoproteins Latent Membrane Protein 1 and 2A.NDRG1 regulates neutral lipid metabolism in breast cancer cells.Effects of Terminal Substitution and Iron Coordination on Antiproliferative Activity of l -Proline-salicylaldehyde-Thiosemicarbazone Hybrids
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The metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 February 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The metastasis suppressor, N-m ...... ced autophagy in cancer cells.
@en
The metastasis suppressor, N-m ...... ced autophagy in cancer cells.
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type
label
The metastasis suppressor, N-m ...... ced autophagy in cancer cells.
@en
The metastasis suppressor, N-m ...... ced autophagy in cancer cells.
@nl
prefLabel
The metastasis suppressor, N-m ...... ced autophagy in cancer cells.
@en
The metastasis suppressor, N-m ...... ced autophagy in cancer cells.
@nl
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P50
P356
P1476
The metastasis suppressor, N-m ...... uced autophagy in cancer cells
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P2093
Patric J Jansson
Zaklina Kovacevic
P2860
P304
P356
10.1074/JBC.M113.529511
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P577
2014-02-15T00:00:00Z