Anti-chemokine small molecule drugs: a promising future?
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The chemokine superfamily revisitedA novel CXCL10-based GPI-anchored fusion protein as adjuvant in NK-based tumor therapyPsychoneuroimmunology meets neuropsychopharmacology: translational implications of the impact of inflammation on behaviorEmerging concepts and approaches for chemokine-receptor drug discovery.Chemokine receptor oligomerization and allostery.The yin and yang of chemokine receptor activation.G protein signaling modulator-3: a leukocyte regulator of inflammation in health and diseaseMonocytes/macrophages express chemokine receptor CCR9 in rheumatoid arthritis and CCL25 stimulates their differentiation.Genetic identity and biological phenotype of a transmitted/founder virus representative of nonpathogenic simian immunodeficiency virus infection in African green monkeysTherapeutic antibodies directed at G protein-coupled receptorsDifferential expression and prognostic value of the chemokine receptor CXCR4 in bronchopulmonary neuroendocrine neoplasms.Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammationFbw7γ-mediated degradation of KLF13 prevents RANTES expression in resting human but not murine T lymphocytes.Nematode asparaginyl-tRNA synthetase resolves intestinal inflammation in mice with T-cell transfer colitis.CCR6 as a possible therapeutic target in psoriasis.Functional inhibition of chemokine receptor CCR2 by dicer-substrate-siRNA prevents pain developmentAnti-inflammatory Agents: Present and FuturePatented biological approaches for the therapeutic modulation of the 37 kDa/67 kDa laminin receptor.Biological therapies in primary Sjögren's syndrome.The complex world of oligodendroglial differentiation inhibitors.Pharmacological modulation of chemokine receptor function.Targeting inflammation in cardiovascular diseases. still a neglected field?Future perspectives: should Th17 cells be considered as a possible therapeutic target in acute myeloid leukemia patients receiving allogeneic stem cell transplantation?Therapeutic potential of chemokine receptor antagonists for liver disease.The role of chemokines in mediating graft versus host disease: opportunities for novel therapeutics.Immunomodulatory effects of antimicrobial agents. Part I: antibacterial and antiviral agents.Chemokines in CNS injury and repair.Progress in the discovery of CC chemokine receptor 2 antagonists, 2009 - 2012.Role of chemokine CCL2 and its receptor CCR2 in neurodegenerative diseases.Chemokine receptors in psoriasis.Chemokine receptor modeling: an interdisciplinary approach to drug design.What Do Structures Tell Us About Chemokine Receptor Function and Antagonism?Molecular Mechanism of Action for Allosteric Modulators and Agonists in CC-chemokine Receptor 5 (CCR5).Elucidation of the CCR1- and CCR5-binding modes of MIP-1α by application of an NMR spectra reconstruction method to the transferred cross-saturation experimentsThe role of chemokines in acute liver injury.A Subset of Patients with Acute Myeloid Leukemia Has Leukemia Cells Characterized by Chemokine Responsiveness and Altered Expression of Transcriptional as well as Angiogenic RegulatorsOptimized dosing of a CCR2 antagonist for amplification of vaccine immunity.Evasin-displaying lactic acid bacteria bind different chemokines and neutralize CXCL8 production in Caco-2 cells.Novel challenges for the allergist.Small molecule CXCR3 antagonist NIBR2130 has only a limited impact on type 1 diabetes in a virus-induced mouse model.
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Anti-chemokine small molecule drugs: a promising future?
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Anti-chemokine small molecule drugs: a promising future?
@en
Anti-chemokine small molecule drugs: a promising future?
@nl
type
label
Anti-chemokine small molecule drugs: a promising future?
@en
Anti-chemokine small molecule drugs: a promising future?
@nl
prefLabel
Anti-chemokine small molecule drugs: a promising future?
@en
Anti-chemokine small molecule drugs: a promising future?
@nl
P2093
P2860
P1476
Anti-chemokine small molecule drugs: a promising future?
@en
P2093
Amanda E I Proudfoot
Christine A Power
Matthias K Schwarz
P2860
P304
P356
10.1517/13543780903535867
P407
P577
2010-03-01T00:00:00Z