Having pancreatic cancer with tumoral loss of ATM and normal TP53 protein expression is associated with a poorer prognosis.
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Is it time to split strategies to treat homologous recombinant deficiency in pancreas cancer?ATM has a major role in the double-strand break repair pathway dysregulation in sporadic breast carcinomas and is an independent prognostic marker at both mRNA and protein levels.Prognostic Significance of Nuclear Phospho-ATM Expression in Melanoma.CHEK2 mutation and risk of prostate cancer: a systematic review and meta-analysis.Safety and Biologic Response of Pre-operative Autophagy Inhibition in Combination with Gemcitabine in Patients with Pancreatic Adenocarcinoma.ATM protein is deficient in over 40% of lung adenocarcinomas.Loss of ataxia-telangiectasia-mutated protein expression correlates with poor prognosis but benefits from anthracycline-containing adjuvant chemotherapy in breast cancer.Individualized radiotherapy (iRT) concepts for locally advanced pancreatic cancer (LAPC): indications and prognostic factors.Epigenetic silencing of EYA2 in pancreatic adenocarcinomas promotes tumor growth.ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancerClonal evolution in relapsed and refractory diffuse large B-cell lymphoma is characterized by high dynamics of subclones.Germline mutations in pancreatic cancer and potential new therapeutic options.Ataxia-Telangiectasia Mutated Modulation of Carbon Metabolism in Cancer.Effect of p53 on pancreatic cancer-glucose tolerance abnormalities by regulating transglutaminase 2 in resistance to glucose metabolic stress.IL2RG, identified as overexpressed by RNA-seq profiling of pancreatic intraepithelial neoplasia, mediates pancreatic cancer growth.Advances in Molecular Profiling and Categorisation of Pancreatic Adenocarcinoma and the Implications for Therapy.Susceptibility of ATM-deficient pancreatic cancer cells to radiation.Impact of p53 and PDGFR-β Expression on Metastasis and Prognosis of Patients with Pancreatic Cancer.Germline Variants and Risk for Pancreatic Cancer: A Systematic Review and Emerging Concepts
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P2860
Having pancreatic cancer with tumoral loss of ATM and normal TP53 protein expression is associated with a poorer prognosis.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 31 January 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Having pancreatic cancer with ...... iated with a poorer prognosis.
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Having pancreatic cancer with ...... iated with a poorer prognosis.
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type
label
Having pancreatic cancer with ...... iated with a poorer prognosis.
@en
Having pancreatic cancer with ...... iated with a poorer prognosis.
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prefLabel
Having pancreatic cancer with ...... iated with a poorer prognosis.
@en
Having pancreatic cancer with ...... iated with a poorer prognosis.
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P2093
P2860
P50
P1476
Having pancreatic cancer with ...... ciated with a poorer prognosis
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P2093
Alison Klein
Burcu Saka
Christopher Wolfgang
Erica Childs
Joseph Herman
Michael Borges
Spencer Knight
P2860
P304
P356
10.1158/1078-0432.CCR-13-1239
P407
P577
2014-01-31T00:00:00Z