Development of a physiologically-based pharmacokinetic model of the rat central nervous system.
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A Generic Multi-Compartmental CNS Distribution Model Structure for 9 Drugs Allows Prediction of Human Brain Target Site ConcentrationsDevelopment of a Region-Specific Physiologically Based Pharmacokinetic Brain Model to Assess Hippocampus and Frontal Cortex Pharmacokinetics.Semi-Mechanistic Population Pharmacokinetic Modeling of L-Histidine Disposition and Brain Uptake in Wildtype and Pht1 Null Mice.Quantitative and Mechanistic Understanding of AZD1775 Penetration across Human Blood-Brain Barrier in Glioblastoma Patients Using an IVIVE-PBPK Modeling Approach.Monoclonal antibody exposure in rat and cynomolgus monkey cerebrospinal fluid following systemic administration.
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Development of a physiologically-based pharmacokinetic model of the rat central nervous system.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 March 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Development of a physiological ...... he rat central nervous system.
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Development of a physiological ...... he rat central nervous system.
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type
label
Development of a physiological ...... he rat central nervous system.
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Development of a physiological ...... he rat central nervous system.
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prefLabel
Development of a physiological ...... he rat central nervous system.
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Development of a physiological ...... he rat central nervous system.
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P1433
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Development of a physiological ...... the rat central nervous system
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Jeffrey I Penny
Marylore Chenel
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P304
P356
10.3390/PHARMACEUTICS6010097
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2014-03-18T00:00:00Z