A novel pharmacologic inhibitor of the NLRP3 inflammasome limits myocardial injury after ischemia-reperfusion in the mouse. - Wikidata - wikimedia - TriplyDB

A novel pharmacologic inhibitor of the NLRP3 inflammasome limits myocardial injury after ischemia-reperfusion in the mouse.

A novel pharmacologic inhibitor of the NLRP3 inflammasome limits myocardial injury after ischemia-reperfusion in the mouse.

http://www.wikidata.org/entity/Q37692892

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Lung inflammation caused by inhaled toxicants: a review Targeting the Innate Immune Response to Improve Cardiac Graft Recovery after Heart Transplantation: Implications for the Donation after Cardiac Death Review of novel therapeutic targets for improving heart failure treatment based on experimental and clinical studies Crosstalk between the heart and peripheral organs in heart failure Innovative Target Therapies Are Able to Block the Inflammation Associated with Dysfunction of the Cholesterol Biosynthesis Pathway NLRP3 inflammasome and its inhibitors: a review Mechanisms of hemorrhagic cystitis.NLRP3 Inflammasome in Neurological Diseases, from Functions to Therapies Interleukin-18 as a therapeutic target in acute myocardial infarction and heart failure.Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectives.Independent roles of the priming and the triggering of the NLRP3 inflammasome in the heart.Pharmacologic Inhibition of the NLRP3 Inflammasome Preserves Cardiac Function After Ischemic and Nonischemic Injury in the Mouse.The Importance of NLRP3 Inflammasome in Heart Failure HMGB1 promotes the activation of NLRP3 and caspase-8 inflammasomes via NF-κB pathway in acute glaucoma.Therapeutics targeting the inflammasome after central nervous system injury.Maladaptive Modulations of NLRP3 Inflammasome and Cardioprotective Pathways Are Involved in Diet-Induced Exacerbation of Myocardial Ischemia/Reperfusion Injury in Mice.AMPK Phosphorylation Modulates Pain by Activation of NLRP3 Inflammasome.Anti-inflammatory interventions-what has worked, not worked, and what may work in the future.Continued Elevation of Interleukin-18 and Interferon-γ After Initiation of Antiretroviral Therapy and Clinical Failure in a Diverse Multicountry Human Immunodeficiency Virus Cohort.PEDF Inhibits the Activation of NLRP3 Inflammasome in Hypoxia Cardiomyocytes through PEDF Receptor/Phospholipase A2.Molecular regulation of cell fate in cerebral ischemia: role of the inflammasome and connected pathways.Targeting danger-associated molecular patterns after myocardial infarction.Sulfonylureas as Concomitant Insulin Secretagogues and NLRP3 Inflammasome Inhibitors.Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance.Interleukin-1 Blockade for the Treatment of Pericarditis.Pharmacological Inhibition of NLRP3 Inflammasome Attenuates Myocardial Ischemia/Reperfusion Injury by Activation of RISK and Mitochondrial Pathways.Treatments for Pulmonary Ricin Intoxication: Current Aspects and Future Prospects.New and revisited approaches to preserving the reperfused myocardium.NLRP3 Inflammasome Mediates Dormant Neutrophil Recruitment following Sterile Lung Injury and Protects against Subsequent Bacterial Pneumonia in Mice.The selective NLRP3-inflammasome inhibitor MCC950 reduces infarct size and preserves cardiac function in a pig model of myocardial infarction.Inflammasomes, the eye and anti-inflammasome therapy.Inflammasomes in neurological diseases: emerging pathogenic and therapeutic concepts.Role of NLRP3 inflammasome in the pathogenesis of cardiovascular diseases.Inflammation following acute myocardial infarction: Multiple players, dynamic roles, and novel therapeutic opportunities.Development and Characterization of a Hydroxyl-Sulfonamide Analogue, 5-Chloro-N-[2-(4-hydroxysulfamoyl-phenyl)-ethyl]-2-methoxy-benzamide, as a Novel NLRP3 Inflammasome Inhibitor for Potential Treatment of Multiple Sclerosis.Mutation in cytochrome b gene of mitochondrial DNA in a family with fibromyalgia is associated with NLRP3-inflammasome activation.NLRP3 (Nucleotide Oligomerization Domain-Like Receptor Family, Pyrin Domain Containing 3)-Caspase-1 Inflammasome Degrades Contractile Proteins: Implications for Aortic Biomechanical Dysfunction and Aneurysm and Dissection Formation.Insights into innate immune signalling in controlling cardiac remodelling.Oxidative Stress and NLRP3-Inflammasome Activity as Significant Drivers of Diabetic Cardiovascular Complications: Therapeutic Implications.NLRP3: A Novel Mediator in Cardiovascular Disease.

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P2860

A novel pharmacologic inhibitor of the NLRP3 inflammasome limits myocardial injury after ischemia-reperfusion in the mouse.

http://www.wikidata.org/entity/Q37692892

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on April 2014

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

A novel pharmacologic inhibito ...... emia-reperfusion in the mouse.

@en

A novel pharmacologic inhibito ...... emia-reperfusion in the mouse.

@nl

type

label

A novel pharmacologic inhibito ...... emia-reperfusion in the mouse.

@en

A novel pharmacologic inhibito ...... emia-reperfusion in the mouse.

@nl

prefLabel

A novel pharmacologic inhibito ...... emia-reperfusion in the mouse.

@en

A novel pharmacologic inhibito ...... emia-reperfusion in the mouse.

@nl

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FJC.0000000000000053

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Journal of Cardiovascular Pharmacology

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A novel pharmacologic inhibito ...... emia-reperfusion in the mouse.

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Antonio Abbate

http://www.w3.org/2001/XMLSchema#string

Benjamin W Van Tassell

http://www.w3.org/2001/XMLSchema#string

Carlo Marchetti

http://www.w3.org/2001/XMLSchema#string

Eleonora Mezzaroma

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Nicla Tranchida

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Scott W Rose

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Shijun Zhang

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Stefano Toldo

http://www.w3.org/2001/XMLSchema#string

P2860

Targeting interleukin-1 in heart disease

Inflammasomes in health and disease

HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte

The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse.

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases.

Effects of interleukin-1 blockade with anakinra on adverse cardiac remodeling and heart failure after acute myocardial infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial (2) (VCU-ART2) pilot study].

Inflammasome-mediated autoinflammatory disorders.

Regulation of the inflammatory response in cardiac repair

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome.

Current status of inflammasome blockers as anti-inflammatory drugs.

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316-322

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scholarly article

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10.1097/FJC.0000000000000053

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4

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63

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Massimo Federici

Jeremy E Chojnacki

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2014-04-01T00:00:00Z

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24336017

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3980088

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