about
Discovery of 5-(4-hydroxyphenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide as a neuroprotectant for Alzheimer's disease by hybridization of curcumin and melatoninPharmacologic Inhibition of the NLRP3 Inflammasome Preserves Cardiac Function After Ischemic and Nonischemic Injury in the Mouse.Bivalent ligand containing curcumin and cholesterol as fluorescence probe for Aβ plaques in Alzheimer's diseaseCurcumin/melatonin hybrid 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide ameliorates AD-like pathology in the APP/PS1 mouse model.Mechanistic Insight of Bivalent Compound 21MO as Potential Neuroprotectant for Alzheimer's DiseaseA novel pharmacologic inhibitor of the NLRP3 inflammasome limits myocardial injury after ischemia-reperfusion in the mouse.Bivalent ligands incorporating curcumin and diosgenin as multifunctional compounds against Alzheimer's disease.Bivalent Compound 17MN Exerts Neuroprotection through Interaction at Multiple Sites in a Cellular Model of Alzheimer's DiseaseNLRP3 Inflammasome Inhibitor Ameliorates Amyloid Pathology in a Mouse Model of Alzheimer's Disease.Design and biological characterization of hybrid compounds of curcumin and thalidomide for multiple myeloma.BF3·OEt2-Promoted Concise Synthesis of Difluoroboron-Derivatized Curcumins from Aldehydes and 2,4-Pentanedione.Inhibition of the NLRP3 inflammasome limits the inflammatory injury following myocardial ischemia-reperfusion in the mouse.Development and Characterization of a Hydroxyl-Sulfonamide Analogue, 5-Chloro-N-[2-(4-hydroxysulfamoyl-phenyl)-ethyl]-2-methoxy-benzamide, as a Novel NLRP3 Inflammasome Inhibitor for Potential Treatment of Multiple Sclerosis.
P50
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P50
description
researcher ORCID id 0000-0003-0202-1895
@en
wetenschapper
@nl
name
Jeremy E Chojnacki
@ast
Jeremy E Chojnacki
@en
Jeremy E Chojnacki
@nl
type
label
Jeremy E Chojnacki
@ast
Jeremy E Chojnacki
@en
Jeremy E Chojnacki
@nl
prefLabel
Jeremy E Chojnacki
@ast
Jeremy E Chojnacki
@en
Jeremy E Chojnacki
@nl
P108
P106
P31
P496
0000-0003-0202-1895