ZEB proteins link cell motility with cell cycle control and cell survival in cancer.
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The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer?MiR-200, a new star miRNA in human cancerCoupled reversible and irreversible bistable switches underlying TGFβ-induced epithelial to mesenchymal transitionThe miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers.Epithelial-mesenchymal transition and tumor suppression are controlled by a reciprocal feedback loop between ZEB1 and Grainyhead-like-2MiR-101 suppresses the epithelial-to-mesenchymal transition by targeting ZEB1 and ZEB2 in ovarian carcinomaRGC32 induces epithelial-mesenchymal transition by activating the Smad/Sip1 signaling pathway in CRC.Members of the microRNA-200 family are promising therapeutic targets in cancer.MicroRNA-708 induces apoptosis and suppresses tumorigenicity in renal cancer cellsZEB2 mediates multiple pathways regulating cell proliferation, migration, invasion, and apoptosis in glioma.Metastatic progression of prostate cancer and e-cadherin regulation by zeb1 and SRC family kinases.The F-box protein Ppa is a common regulator of core EMT factors Twist, Snail, Slug, and Sip1Cooperative effects of Akt-1 and Raf-1 on the induction of cellular senescence in doxorubicin or tamoxifen treated breast cancer cells.Epithelial-mesenchymal transition in ovarian carcinomaThe transcription factor Zeb2 regulates signaling in mast cellsMesenchymal traits are selected along with stem features in breast cancer cells grown as mammospheres.A link between lipid metabolism and epithelial-mesenchymal transition provides a target for colon cancer therapy.Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response.FOXL1, a novel candidate tumor suppressor, inhibits tumor aggressiveness and predicts outcome in human pancreatic cancer.Heterozygous deletions at the ZEB1 locus verify haploinsufficiency as the mechanism of disease for posterior polymorphous corneal dystrophy type 3.Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells.Mesenchymal marker expression is elevated in Müller cells exposed to high glucose and in animal models of diabetic retinopathy.Emerging role for epithelial polarity proteins of the Crumbs family as potential tumor suppressors.MicroRNA Control of Invasion and Metastasis Pathways.The metastatic niche and stromal progression.ZEB/miR-200 feedback loop: at the crossroads of signal transduction in cancer.EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness.EMT transcription factors: implication in osteosarcoma.Epithelial to mesenchymal transition inducing transcription factors and metastatic cancer.Molecular pathways: linking tumor microenvironment to epithelial-mesenchymal transition in metastasis.ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression.Lethal (2) giant larvae: an indispensable regulator of cell polarity and cancer development.Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells.miR-200c: a versatile watchdog in cancer progression, EMT, and drug resistance.MicroRNA-19 triggers epithelial-mesenchymal transition of lung cancer cells accompanied by growth inhibition.Overexpression of zinc finger E-box binding homeobox factor 1 promotes tumor invasiveness and confers unfavorable prognosis in esophageal squamous cell carcinoma.MiR-141 targets ZEB2 to suppress HCC progression.An alternative promoter of the human plakophilin-3 gene controls the expression of the new isoform PKP3b.Establishment of a Chinese bladder cancer cell line (T921) with high metastatic activity.MiR-520h-mediated FOXC2 regulation is critical for inhibition of lung cancer progression by resveratrol.
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ZEB proteins link cell motility with cell cycle control and cell survival in cancer.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 03 March 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
ZEB proteins link cell motility with cell cycle control and cell survival in cancer.
@en
ZEB proteins link cell motility with cell cycle control and cell survival in cancer.
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type
label
ZEB proteins link cell motility with cell cycle control and cell survival in cancer.
@en
ZEB proteins link cell motility with cell cycle control and cell survival in cancer.
@nl
prefLabel
ZEB proteins link cell motility with cell cycle control and cell survival in cancer.
@en
ZEB proteins link cell motility with cell cycle control and cell survival in cancer.
@nl
P356
P1433
P1476
ZEB proteins link cell motility with cell cycle control and cell survival in cancer
@en
P2093
Eugene Tulchinsky
Gareth Browne
P304
P356
10.4161/CC.9.5.10839
P50
P577
2010-03-03T00:00:00Z