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Targeting cancer using KAT inhibitors to mimic lethal knockoutsThe Knowns Unknowns: Exploring the Homologous Recombination Repair Pathway in Toxoplasma gondiiATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to AdaptorKATs in cancer: functions and therapiesPharmacological modulators of the circadian clock as potential therapeutic drugs: focus on genotoxic/anticancer therapyCrosstalk between ubiquitin and other post-translational modifications on chromatin during double-strand break repairThe DNA Damage Response: Making It Safe to Play with KnivesAcetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and CancerRoles of N-Myc and STAT interactor in cancer: From initiation to disseminationThe acetyltransferase Tip60 is a critical regulator of the differentiation-dependent amplification of human papillomaviruses.Histone deacetylase 10 regulates DNA mismatch repair and may involve the deacetylation of MutS homolog 2.Deubiquitination of Tip60 by USP7 determines the activity of the p53-dependent apoptotic pathwayRVBs are required for assembling a functional TIP60 complexChromatin modifications during repair of environmental exposure-induced DNA damage: a potential mechanism for stable epigenetic alterations.A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy.DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatin.SUMOylation and de-SUMOylation in response to DNA damage.Microarray analysis uncovers a role for Tip60 in nervous system function and general metabolismMitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition.CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes.A polymorphism in JMJD2C alters the cleavage by caspase-3 and the prognosis of human breast cancer.The MRN complex in double-strand break repair and telomere maintenance.Loss of nonsense mediated decay suppresses mutations in Saccharomyces cerevisiae TRA1DNA methyltransferase 1(DNMT1) induced the expression of suppressors of cytokine signaling3 (Socs3) in a mouse model of asthma.Targeting of DNA Damage Signaling Pathway Induced Senescence and Reduced Migration of Cancer cells.Bromodomain coactivators in cancer, obesity, type 2 diabetes, and inflammationStructure and mechanisms of lysine methylation recognition by the chromodomain in gene transcription.Dynamics of double strand breaks and chromosomal translocationsNucleotide excision repair efficiency in quiescent human fibroblasts is modulated by circadian clockIdentification of the interactors of human nibrin (NBN) and of its 26 kDa and 70 kDa fragments arising from the NBN 657del5 founder mutation.Protein acetylation and agingThe radioprotective agent WR1065 protects cells from radiation damage by regulating the activity of the Tip60 acetyltransferaseATP hydrolysis by RAD50 protein switches MRE11 enzyme from endonuclease to exonuclease.Changing the ubiquitin landscape during viral manipulation of the DNA damage response.Genetic evidence links the ASTRA protein chaperone component Tti2 to the SAGA transcription factor Tra1.DNA transcription and repair: a confluenceAntagonistic Relationship between Human Cytomegalovirus pUL27 and pUL97 Activities during Infection.Depletion of Tip60 from In Vivo Cardiomyocytes Increases Myocyte Density, Followed by Cardiac Dysfunction, Myocyte Fallout and Lethality.Ataxia telangiectasia mutated (ATM) interacts with p400 ATPase for an efficient DNA damage response.The Epstein-Barr Virus Immunoevasins BCRF1 and BPLF1 Are Expressed by a Mechanism Independent of the Canonical Late Pre-initiation Complex.
P2860
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P2860
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 11 March 2010
@en
vedecký článok
@sk
vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Tip60: connecting chromatin to DNA damage signaling.
@en
Tip60: connecting chromatin to DNA damage signaling.
@nl
type
label
Tip60: connecting chromatin to DNA damage signaling.
@en
Tip60: connecting chromatin to DNA damage signaling.
@nl
prefLabel
Tip60: connecting chromatin to DNA damage signaling.
@en
Tip60: connecting chromatin to DNA damage signaling.
@nl
P2093
P2860
P356
P1433
P1476
Tip60: connecting chromatin to DNA damage signaling.
@en
P2093
Brendan D Price
Xiaofeng Jiang
Yingli Sun
P2860
P304
P356
10.4161/CC.9.5.10931
P577
2010-03-11T00:00:00Z