Deubiquitination of Tip60 by USP7 determines the activity of the p53-dependent apoptotic pathway
about
DUBbing Cancer: Deubiquitylating Enzymes Involved in Epigenetics, DNA Damage and the Cell Cycle As Therapeutic TargetsRegulation of Mutant p53 Protein ExpressionRole of Deubiquitinating Enzymes in DNA RepairModulation of the p53/MDM2 interplay by HAUSP inhibitorsp53 Acetylation: Regulation and ConsequencesCRL4Cdt2 E3 ubiquitin ligase and proliferating cell nuclear antigen (PCNA) cooperate to degrade thymine DNA glycosylase in S phase14-3-3 proteins play a role in the cell cycle by shielding cdt2 from ubiquitin-mediated degradationNuclear matrix protein SMAR1 represses c-Fos-mediated HPV18 E6 transcription through alteration of chromatin histone deacetylationMolecular mechanism for USP7-mediated DNMT1 stabilization by acetylation.Molecular pathways: turning proteasomal protein degradation into a unique treatment approach.USP7 Enforces Heterochromatinization of p53 Target Promoters by Protecting SUV39H1 from MDM2-Mediated Degradation.Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3+ T-regulatory Cell Function and Promotes Antitumor Immunity.Selective and reversible inhibitors of ubiquitin-specific protease 7: a patent evaluation (WO2013030218).Cell death and deubiquitinases: perspectives in cancer.TIPping the balance in adipogenesis: USP7-mediated stabilization of Tip60.Ubiquitin-specific peptidase 7 (USP7)-mediated deubiquitination of the histone deacetylase SIRT7 regulates gluconeogenesis.The stress-responsive gene ATF3 regulates the histone acetyltransferase Tip60.Activity-based probes for the ubiquitin conjugation-deconjugation machinery: new chemistries, new tools, and new insights.Termination of DNA replication forks: "Breaking up is hard to do".Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60.Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60.Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.Molecular basis of USP7 inhibition by selective small-molecule inhibitors.The human T-cell leukemia virus type-1 p30II protein activates p53 and induces the TIGAR and suppresses oncogene-induced oxidative stress during viral carcinogenesis.Ubiquitin Regulation: The Histone Modifying Enzyme's Story
P2860
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P2860
Deubiquitination of Tip60 by USP7 determines the activity of the p53-dependent apoptotic pathway
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Deubiquitination of Tip60 by U ...... 53-dependent apoptotic pathway
@ast
Deubiquitination of Tip60 by U ...... 53-dependent apoptotic pathway
@en
type
label
Deubiquitination of Tip60 by U ...... 53-dependent apoptotic pathway
@ast
Deubiquitination of Tip60 by U ...... 53-dependent apoptotic pathway
@en
prefLabel
Deubiquitination of Tip60 by U ...... 53-dependent apoptotic pathway
@ast
Deubiquitination of Tip60 by U ...... 53-dependent apoptotic pathway
@en
P2860
P356
P1476
Deubiquitination of Tip60 by U ...... 53-dependent apoptotic pathway
@en
P2093
Ashraf Dar
P2860
P304
P356
10.1128/MCB.00358-13
P407
P577
2013-06-17T00:00:00Z