The signaling lipid PI(3,5)P₂ stabilizes V₁-V(o) sector interactions and activates the V-ATPase
about
The Fab1/PIKfyve phosphoinositide phosphate kinase is not necessary to maintain the pH of lysosomes and of the yeast vacuole.Affinity Purification and Structural Features of the Yeast Vacuolar ATPase Vo Membrane Sector.Structure of the Lipid Nanodisc-reconstituted Vacuolar ATPase Proton Channel: DEFINITION OF THE INTERACTION OF ROTOR AND STATOR AND IMPLICATIONS FOR ENZYME REGULATION BY REVERSIBLE DISSOCIATION.What are the roles of V-ATPases in membrane fusion?Perturbation of the Vacuolar ATPase: A NOVEL CONSEQUENCE OF INOSITOL DEPLETIONEarly to Late Endosome Trafficking Controls Secretion and Zymogen Activation in Rodent and Human Pancreatic Acinar Cells.The yeast protein kinase Sch9 adjusts V-ATPase assembly/disassembly to control pH homeostasis and longevity in response to glucose availabilityPhosphatidylinositol 3,5-bisphosphate: regulation of cellular events in space and time.A cell-permeable tool for analysing APP intracellular domain function and manipulation of PIKfyve activity.Saccharomyces cerevisiae vacuolar H+-ATPase regulation by disassembly and reassembly: one structure and multiple signals.Lipids implicated in the journey of a secretory granule: from biogenesis to fusion.Recent Insights into the Structure, Regulation, and Function of the V-ATPasesPIKfyve activity regulates reformation of terminal storage lysosomes from endolysosomes.Proton Transport and pH Control in Fungi.Regulation of V-ATPase assembly and function of V-ATPases in tumor cell invasiveness.The signaling lipid phosphatidylinositol-3,5-bisphosphate targets plant CLC-a anion/H+ exchange activity.Phosphatidylinositol 3,5-Bisphosphate-Rich Membrane Domains in Endosomes and Lysosomes.Target of rapamycin signaling mediates vacuolar fragmentation.PI5P and PI(3,5)P2: Minor, but Essential Phosphoinositides.Direct interaction of the Golgi V-ATPase a-subunit isoform with PI(4)P drives localization of Golgi V-ATPases in yeast.Evidence for ESCRT- and clathrin-dependent microautophagy.Phosphatidylinositol 3,5-bisphosphate is involved in methylglyoxal-induced activation of the Mpk1 mitogen-activated protein kinase cascade in Saccharomyces cerevisiae.DepHining membrane identity.Biolayer interferometry of lipid nanodisc-reconstituted yeast vacuolar H+ -ATPase.Early protection to stress mediated by CDK-dependent PI3,5P2 signaling from the vacuole/lysosome.Phosphoinositide conversion in endocytosis and the endolysosomal system.pH homeostasis links the nutrient sensing PKA/TORC1/Sch9 ménage-à-trois to stress tolerance and longevity.Control of vacuole membrane homeostasis by a resident PI-3,5-kinase inhibitor.Regulation of V-ATPase Assembly in Nutrient Sensing and Function of V-ATPases in Breast Cancer MetastasisPI(3,5)P controls vacuole potassium transport to support cellular osmoregulation
P2860
Q27314340-B73247D0-151C-49C8-A51A-EBD7B71CD81AQ30379694-1BD7A04B-5366-4331-8DB2-C94938D80962Q30396376-C6F3C8C9-5D55-4EB4-B1DD-5D3131E67FF8Q34925693-FD574E73-512C-4640-A027-05606ED6E28FQ36282823-7B6B466F-3E88-43F0-8BD0-A38DF0C62D27Q36310514-03D3025A-27BC-4256-9F4E-68D3DF749ADEQ36399070-BF6DB82A-20BB-4214-AECA-3D9DBEFDE56FQ36812142-489BCD11-4EE7-423A-8FC3-494073B94B79Q37626840-CC6820B7-4A74-47D5-AC03-038A0A1C0158Q38202559-E642019E-F62C-4E16-A072-189EF2D2E094Q38560548-EC9DD2DF-E2F0-485B-BD36-44CD616173BBQ38593788-662032D4-F474-4F13-9C5C-6F296056824FQ38600541-A543D3CE-088E-41EF-9818-3408A1AFDA91Q38684254-C86DAD31-103A-4365-89C4-E5D29F7AEFC6Q38746834-9895524B-A5CD-4E12-840C-B049468E97B3Q38768292-54C96690-46A6-48AB-9682-287EC64F7F11Q38819806-2A8A513A-FCB2-4E60-9050-8BA729B9744EQ38846161-73F254CB-C34E-475E-B89A-FBDC1C89E60CQ39182894-4F6CBDE5-64CB-4DCC-BD31-D771DF9E6DCBQ46334211-5E0E52F3-5A94-4B77-AF80-C10ACAB3ECA5Q47909119-73E48B12-20F6-4B23-A1B0-4258552BE8E1Q48028332-C4DB4C4A-2FC6-4410-9110-B606C7E02FDCQ48131243-1FD5AA42-FC1F-4341-BF85-6D0B08599BEFQ48189738-ABC69202-3FC2-4A95-AC47-E731AB2F282FQ48241853-CEC5D400-B0FC-415D-A5E6-23167F680D1DQ49547382-7C53AB51-C88C-4602-A01F-3DD2D4E57731Q50316174-DC78AC80-9477-491A-8527-737A138C9EA3Q52315057-36240F45-9834-48EA-8F01-89148A49D41EQ57109591-35FD5476-78C4-49CA-AE69-29D4A71391BAQ58298746-D7AF3D3C-5770-4E20-A37E-97764BE0DD8C
P2860
The signaling lipid PI(3,5)P₂ stabilizes V₁-V(o) sector interactions and activates the V-ATPase
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 February 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The signaling lipid PI(3,5)P₂ ...... ons and activates the V-ATPase
@en
The signaling lipid PI(3,5)P₂ ...... ns and activates the V-ATPase.
@nl
type
label
The signaling lipid PI(3,5)P₂ ...... ons and activates the V-ATPase
@en
The signaling lipid PI(3,5)P₂ ...... ns and activates the V-ATPase.
@nl
prefLabel
The signaling lipid PI(3,5)P₂ ...... ons and activates the V-ATPase
@en
The signaling lipid PI(3,5)P₂ ...... ns and activates the V-ATPase.
@nl
P2093
P2860
P356
P1476
The signaling lipid PI(3,5)P₂ ...... ons and activates the V-ATPase
@en
P2093
Lois S Weisman
Maureen Tarsio
Patricia M Kane
Sergio Couoh-Cardel
Theodore T Diakov
P2860
P304
P356
10.1091/MBC.E13-10-0563
P577
2014-02-12T00:00:00Z