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The Interplay of Reactive Oxygen Species, Hypoxia, Inflammation, and Sirtuins in Cancer Initiation and ProgressionPathophysiology of osteoarthritis: canonical NF-κB/IKKβ-dependent and kinase-independent effects of IKKα in cartilage degradation and chondrocyte differentiationEmerging regulators of the inflammatory process in osteoarthritisCurcumin slows osteoarthritis progression and relieves osteoarthritis-associated pain symptoms in a post-traumatic osteoarthritis mouse modelTranscriptome-wide gene regulation by gentle treadmill walking during the progression of monoiodoacetate-induced arthritis.Caesalpinia sappan extract inhibits IL1β-mediated overexpression of matrix metalloproteinases in human chondrocytes.Immunopathogenesis of osteoarthritisHuman osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1β-stimulated production of chemokines and matrix-degrading enzymes in vitro.The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis.Signaling pathways in cartilage repair.Collagen-derived N-acetylated proline-glycine-proline upregulates the expression of pro-inflammatory cytokines and extracellular matrix proteases in nucleus pulposus cells via the NF-κB and MAPK signaling pathways.MicroRNAs and Autophagy: Fine Players in the Control of Chondrocyte Homeostatic Activities in Osteoarthritis.Effects of TLR-2/NF-κB signaling pathway on the occurrence of degenerative knee osteoarthritis: an in vivo and in vitro study.Effect of a Herbal-Leucine mix on the IL-1β-induced cartilage degradation and inflammatory gene expression in human chondrocytes.Differential gene expression of the intermediate and outer interzone layers of developing articular cartilage in murine embryos.CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation-Resistant Tissues.Biological aspects of early osteoarthritis.Joint pathology and platelet-rich plasma therapies.Current nutraceuticals in the management of osteoarthritis: a reviewNuclear factor (NF)-κB and its associated pathways are major molecular regulators of blood-induced joint damage in a murine model of hemophilia.Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical TrialsProtective effects of biochanin A on articular cartilage: in vitro and in vivo studies.Differential response of chondrocytes and chondrogenic-induced mesenchymal stem cells to C1-OH tributanoylated N-acetylhexosamines.IKKα/CHUK regulates extracellular matrix remodeling independent of its kinase activity to facilitate articular chondrocyte differentiation.Use of cartilage derived from murine induced pluripotent stem cells for osteoarthritis drug screening.6-gingerol protects against nutritional steatohepatitis by regulating key genes related to inflammation and lipid metabolism.Role of NF-κB in the skeletonInhibition of inflammatory arthritis using fullerene nanomaterials.Connexin43 enhances the expression of osteoarthritis-associated genes in synovial fibroblasts in culture.The involvement of follistatin-like protein 1 in osteoarthritis by elevating NF-κB-mediated inflammatory cytokines and enhancing fibroblast like synoviocyte proliferation.Epigallocatechin-3-gallate suppresses the global interleukin-1beta-induced inflammatory response in human chondrocytes.Emerging targets in osteoarthritis therapy.Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritisArticular cartilage degradation in osteoarthritis.Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint healthA New Application of Parallel Synthesis Strategy for Discovery of Amide-Linked Small Molecules as Potent Chondroprotective Agents in TNF-α-Stimulated Chondrocytes.The role of synovitis in osteoarthritis pathogenesisIn vitro effects of platelet-rich gel supernatants on histology and chondrocyte apoptosis scores, hyaluronan release and gene expression of equine cartilage explants challenged with lipopolysaccharide.Chondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritis.Update on biological therapies for knee injuries: osteoarthritis.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
NF-kappaB signaling: multiple angles to target OA.
@en
NF-kappaB signaling: multiple angles to target OA.
@nl
type
label
NF-kappaB signaling: multiple angles to target OA.
@en
NF-kappaB signaling: multiple angles to target OA.
@nl
prefLabel
NF-kappaB signaling: multiple angles to target OA.
@en
NF-kappaB signaling: multiple angles to target OA.
@nl
P2093
P2860
P1433
P1476
NF-kappaB signaling: multiple angles to target OA
@en
P2093
Kenneth B Marcu
Mary B Goldring
Miguel Otero
Rosa Maria Borzi
P2860
P304
P356
10.2174/138945010791011938
P577
2010-05-01T00:00:00Z