Is cartilage matrix breakdown an appropriate therapeutic target in osteoarthritis--insights from studies of aggrecan and collagen proteolysis?
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Genetically Engineered Mouse Models Reveal the Importance of Proteases as Osteoarthritis Drug TargetsDetecting early stage osteoarthritis by optical coherence tomography?Pre-Osteoarthritis: Definition and Diagnosis of an Elusive Clinical EntitySubchondral bone trabecular integrity predicts and changes concurrently with radiographic and magnetic resonance imaging-determined knee osteoarthritis progression.Verapamil protects against cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signalingProteases involved in cartilage matrix degradation in osteoarthritis.Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritisArticular cartilage degradation in osteoarthritis.Chondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritis.Do mouse models reflect the diversity of osteoarthritis in humans?Nanoparticles for improved local retention after intra-articular injection into the knee joint.Therapeutic effects of an anti-ADAMTS-5 antibody on joint damage and mechanical allodynia in a murine model of osteoarthritis.A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotypemicroRNA-140 Inhibits Inflammation and Stimulates Chondrogenesis in a Model of Interleukin 1β-induced Osteoarthritis.Deferoxamine Suppresses Collagen Cleavage and Protease, Cytokine, and COL10A1 Expression and Upregulates AMPK and Krebs Cycle Genes in Human Osteoarthritic Cartilage.Inflammation in osteoarthritis.Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis.Novel Insights into Osteoarthritis Joint Pathology from Studies in Mice.Developmental mechanisms in articular cartilage degradation in osteoarthritisRecent advances in the understanding of molecular mechanisms of cartilage degeneration, synovitis and subchondral bone changes in osteoarthritis.Using mouse models to investigate the pathophysiology, treatment, and prevention of post-traumatic osteoarthritis.The biology of meniscal pathology in osteoarthritis and its contribution to joint disease: beyond simple mechanics.Models to define the stages of articular cartilage degradation in osteoarthritis development.MicroRNA-140 and the silencing of osteoarthritisInfluence of six medicinal herbs on collagenase-induced osteoarthritis in rats.
P2860
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P2860
Is cartilage matrix breakdown an appropriate therapeutic target in osteoarthritis--insights from studies of aggrecan and collagen proteolysis?
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on May 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Is cartilage matrix breakdown ...... ecan and collagen proteolysis?
@en
Is cartilage matrix breakdown ...... ecan and collagen proteolysis?
@nl
type
label
Is cartilage matrix breakdown ...... ecan and collagen proteolysis?
@en
Is cartilage matrix breakdown ...... ecan and collagen proteolysis?
@nl
prefLabel
Is cartilage matrix breakdown ...... ecan and collagen proteolysis?
@en
Is cartilage matrix breakdown ...... ecan and collagen proteolysis?
@nl
P921
P1433
P1476
Is cartilage matrix breakdown ...... ecan and collagen proteolysis?
@en
P2093
Amanda J Fosang
Christopher B Little
P304
P356
10.2174/138945010791011956
P577
2010-05-01T00:00:00Z