Pre-clinical evidence that corticotropin-releasing factor (CRF) receptor antagonists are promising targets for pharmacological treatment of alcoholism.
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Natural rewards, neuroplasticity, and non-drug addictionsEffects of alcohol dependence and withdrawal on stress responsiveness and alcohol consumptionGlucocorticoid and polyamine interactions in the plasticity of glutamatergic synapses that contribute to ethanol-associated dependence and neuronal injuryUrocortins: CRF's siblings and their potential role in anxiety, depression and alcohol drinking behavior.Synaptic effects induced by alcohol.Targeting psychologic stress signaling pathways in Alzheimer's disease.Type 7 Adenylyl Cyclase is Involved in the Ethanol and CRF Sensitivity of GABAergic Synapses in Mouse Central Amygdala.Chronic alcohol exposure differentially affects activation of female locus coeruleus neurons and the subcellular distribution of corticotropin releasing factor receptors.Amygdalar neuronal plasticity and the interactions of alcohol, sex, and stress.Dissociation of μ-opioid receptor and CRF-R1 antagonist effects on escalated ethanol consumption and mPFC serotonin in C57BL/6J mice.Pharmacological blockade of corticotropin-releasing hormone receptor 1 (CRH1R) reduces voluntary consumption of high alcohol concentrations in non-dependent Wistar rats.Commentary: studies on binge-like ethanol drinking may help to identify the neurobiological mechanisms underlying the transition to dependence.Corticotropin releasing factor signaling in the central amygdala is recruited during binge-like ethanol consumption in C57BL/6J miceEthanol concentration-dependent effects and the role of stress on ethanol drinking in corticotropin-releasing factor type 1 and double type 1 and 2 receptor knockout miceRole of corticotropin-releasing factor and corticosterone in behavioral sensitization to ethanolEffects of the combination of metyrapone and oxazepam on intravenous nicotine self-administration in rats.Alcohol in excess: CRF₁ receptors in the rat and mouse VTA and DRN.Preclinical evidence implicating corticotropin-releasing factor signaling in ethanol consumption and neuroadaptation.CRF1 receptor signaling regulates food and fluid intake in the drinking-in-the-dark model of binge alcohol consumption.Early life stress is a risk factor for excessive alcohol drinking and impulsivity in adults and is mediated via a CRF/GABA(A) mechanismCoordinate regulation of noradrenergic and serotonergic brain regions by amygdalar neuronsControl of chronic excessive alcohol drinking by genetic manipulation of the Edinger-Westphal nucleus urocortin-1 neuropeptide system.Binge ethanol-drinking potentiates corticotropin releasing factor R1 receptor activity in the ventral tegmental area.Does midbrain urocortin 1 matter? A 15-year journey from stress (mal)adaptation to energy metabolism.Ethanol and corticotropin releasing factor receptor modulation of central amygdala neurocircuitry: An update and future directions.Influence of stress associated with chronic alcohol exposure on drinking.Extended Amygdala to Ventral Tegmental Area Corticotropin-Releasing Factor Circuit Controls Binge Ethanol Intake.Novel Roles for CRF-Binding Protein and CRF Receptor 2 in Binge Drinking.Histamine h3 receptor: a novel therapeutic target in alcohol dependence?Binge Drinking Decreases Corticotropin-Releasing Factor-Binding Protein Expression in the Medial Prefrontal Cortex of Mice.Cytokine involvement in stress may depend on corticotrophin releasing factor to sensitize ethanol withdrawal anxiety.Corticotropin-releasing factor: innocent until proven guilty.Chronic psychosocial stress causes delayed extinction and exacerbates reinstatement of ethanol-induced conditioned place preference in mice.Corticotropin Releasing Factor in the Bed Nucleus of the Stria Terminalis in Socially Defeated and Non-stressed Mice with a History of Chronic Alcohol Intake.Serotonergic Neuroplasticity in Alcohol Addiction.
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Pre-clinical evidence that corticotropin-releasing factor (CRF) receptor antagonists are promising targets for pharmacological treatment of alcoholism.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on March 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Pre-clinical evidence that cor ...... gical treatment of alcoholism.
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Pre-clinical evidence that corticotropin-releasing factor
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type
label
Pre-clinical evidence that cor ...... gical treatment of alcoholism.
@en
Pre-clinical evidence that corticotropin-releasing factor
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prefLabel
Pre-clinical evidence that cor ...... gical treatment of alcoholism.
@en
Pre-clinical evidence that corticotropin-releasing factor
@nl
P2860
P1476
Pre-clinical evidence that cor ...... gical treatment of alcoholism.
@en
P2093
Emily G Lowery
Todd E Thiele
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P356
10.2174/187152710790966605
P577
2010-03-01T00:00:00Z