A review of LC-MS techniques and high-throughput approaches used to investigate drug metabolism by cytochrome P450s.

A review of LC-MS techniques and high-throughput approaches used to investigate drug metabolism by cytochrome P450s.

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http://www.wikidata.org/entity/Q37703851
Liquid chromatography/quadrupole time-of-flight mass spectrometry in combination with online hydrogen/deuterium exchange technique for structural elucidation of phase I metabolites of iso-phenylcyclopentylamine in rat bile.Rapid and quantitative measurement of metabolic stability without chromatography or mass spectrometryDevelopment of a High-Throughput and Miniaturized Cytokinesis-Block Micronucleus Assay for Use as a Biological Dosimetry Population Triage Tool.Chronic administration of caderofloxacin, a new fluoroquinolone, increases hepatic CYP2E1 expression and activity in ratsSPE-MS analysis of absorption, distribution, metabolism and excretion assays: a tool to increase throughput and steamline workflow.Direct bioanalytical sample injection with 2D LC-MS.Multiple stage MS in analysis of plasma, serum, urine and in vitro samples relevant to clinical and forensic toxicology.Combination of on-line CE assay with MS detection for the study of drug metabolism by cytochromes P450.In vitro and in vivo metabolism of N-adamantyl substituted urea-based soluble epoxide hydrolase inhibitors.Phase I and phase II reductive metabolism simulation of nitro aromatic xenobiotics with electrochemistry coupled with high resolution mass spectrometry.Is zebrafish (Danio rerio) a tool for human-like metabolism study?Metabolic profile of salidroside in rats using high-performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry.Cytochromes P450 as useful biocatalysts: addressing the limitations
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A review of LC-MS techniques and high-throughput approaches used to investigate drug metabolism by cytochrome P450s.

Item
http://www.wikidata.org/entity/Q37703851
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 17 February 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A review of LC-MS techniques a ...... etabolism by cytochrome P450s.
@en
A review of LC-MS techniques a ...... etabolism by cytochrome P450s.
@nl
type
label
A review of LC-MS techniques a ...... etabolism by cytochrome P450s.
@en
A review of LC-MS techniques a ...... etabolism by cytochrome P450s.
@nl
prefLabel
A review of LC-MS techniques a ...... etabolism by cytochrome P450s.
@en
A review of LC-MS techniques a ...... etabolism by cytochrome P450s.
@nl
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A review of LC-MS techniques a ...... etabolism by cytochrome P450s.
@en
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P356
10.1016/J.JCHROMB.2010.02.013
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P577
P698