A new paradigm for the role of aging in the development of skin cancer.
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Fibroblasts derived from human embryonic stem cells direct development and repair of 3D human skin equivalentsSkin resurfacing procedures: new and emerging optionsThe IGF-1/IGF-1R signaling axis in the skin: a new role for the dermis in aging-associated skin cancer.Fibroblast senescence and squamous cell carcinoma: how wounding therapies could be protective.Fractionated laser resurfacing corrects the inappropriate UVB response in geriatric skinMice lacking epidermal PPARγ exhibit a marked augmentation in photocarcinogenesis associated with increased UVB-induced apoptosis, inflammation and barrier dysfunctionInsulin-like growth factor I (IGF-1) Ec/Mechano Growth factor--a splice variant of IGF-1 within the growth plate.Reversing the aging stromal phenotype prevents carcinoma initiationHost age is a systemic regulator of gene expression impacting cancer progressionHow Wounding via Lasers Has Potential Photocarcinogenic Preventative Effects via Dermal Remodeling.Tumor-host signaling interaction reveals a systemic, age-dependent splenic immune influence on tumor development.Impact of Age and Insulin-Like Growth Factor-1 on DNA Damage Responses in UV-Irradiated Human Skin.Insulin-like growth factor-1 receptor regulates repair of ultraviolet B-induced DNA damage in human keratinocytes in vivo.Insulin-like Growth Factor 1 Receptor Signaling Is Required for Optimal ATR-CHK1 Kinase Signaling in Ultraviolet B (UVB)-irradiated Human Keratinocytes.Roles of UVA radiation and DNA damage responses in melanoma pathogenesis.
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A new paradigm for the role of aging in the development of skin cancer.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 25 September 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A new paradigm for the role of aging in the development of skin cancer.
@en
A new paradigm for the role of aging in the development of skin cancer.
@nl
type
label
A new paradigm for the role of aging in the development of skin cancer.
@en
A new paradigm for the role of aging in the development of skin cancer.
@nl
prefLabel
A new paradigm for the role of aging in the development of skin cancer.
@en
A new paradigm for the role of aging in the development of skin cancer.
@nl
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P1476
A new paradigm for the role of aging in the development of skin cancer.
@en
P2093
Dan F Spandau
Davina A Lewis
Jeffrey B Travers
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P2888
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10.1038/JID.2008.293
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P577
2008-09-25T00:00:00Z