Efflux and uptake transporters as determinants of statin response.
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Statin-associated muscle symptoms: impact on statin therapy-European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and ManagementPharmacogenetic Foundations of Therapeutic Efficacy and Adverse Events of Statins.Association of CYP2D6*10, OATP1B1 A388G, and OATP1B1 T521C polymorphisms and overall survival of breast cancer patients after tamoxifen therapyPharmacogenetics of OATP transporters reveals that SLCO1B1 c.388A>G variant is determinant of increased atorvastatin responseTreatment Options for Statin-Associated Muscle Symptoms.Molecular mechanisms of statin intoleranceTransporter pharmacogenetics: transporter polymorphisms affect normal physiology, diseases, and pharmacotherapyThe ABCG2 transporter and its relations with the pharmacokinetics, drug interaction and lipid-lowering effects of statins.Genetic variations of bile salt transporters as predisposing factors for drug-induced cholestasis, intrahepatic cholestasis of pregnancy and therapeutic response of viral hepatitis.Impact of SLCO1B1 (OATP1B1) and ABCG2 (BCRP) genetic polymorphisms and inhibition on LDL-C lowering and myopathy of statins.Pharmacogenetics of drug transporters in the enterohepatic circulation.Drug safety evaluation of rosuvastatin.Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro-in vivo extrapolation of oral drug absorption.Pharmacogenomics of lipid-lowering therapies.Lipid-lowing pharmacogenomics in Chinese patients.Minireview: SLCO and ABC transporters: a role for steroid transport in prostate cancer progression.Atorvastatin attenuation of ABCB1 expression is mediated by microRNA miR-491-3p in Caco-2 cells.Fusidic Acid Inhibits Hepatic Transporters and Metabolic Enzymes: Potential Cause of Clinical Drug-Drug Interaction Observed with Statin Coadministration.Genetic variation in the ABCC2 gene is associated with dose decreases or switches to other cholesterol-lowering drugs during simvastatin and atorvastatin therapy.Simvastatin activates single skeletal RyR1 channels but exerts more complex regulation of the cardiac RyR2 isoform.Differential effect of genetic variants of Na(+)-taurocholate co-transporting polypeptide (NTCP) and organic anion-transporting polypeptide 1B1 (OATP1B1) on the uptake of HMG-CoA reductase inhibitors.Genetic variation in statin intolerance and a possible protective role for UGT1A1.Synergistic inhibitory effect of apomine and lovastatin on osteosarcoma cell growth.No impact of SLCO1B1 521T>C, 388A>G and 411G>A polymorphisms on response to statin therapy in the Greek population.Interactions Between Genotype and Preoperative Statin Use Impact Clinical Outcomes Among Breast Cancer Patients
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P2860
Efflux and uptake transporters as determinants of statin response.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on May 2010
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Efflux and uptake transporters as determinants of statin response.
@en
Efflux and uptake transporters as determinants of statin response.
@nl
type
label
Efflux and uptake transporters as determinants of statin response.
@en
Efflux and uptake transporters as determinants of statin response.
@nl
prefLabel
Efflux and uptake transporters as determinants of statin response.
@en
Efflux and uptake transporters as determinants of statin response.
@nl
P2860
P1476
Efflux and uptake transporters as determinants of statin response
@en
P2093
Alice C Rodrigues
P2860
P304
P356
10.1517/17425251003713519
P407
P577
2010-05-01T00:00:00Z