The pivotal roles of mitochondria in cancer: Warburg and beyond and encouraging prospects for effective therapies.
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The Warburg effect and drug resistanceMethyl jasmonate: putative mechanisms of action on cancer cells cycle, metabolism, and apoptosisAnalysis and interpretation of transcriptomic data obtained from extended Warburg effect genes in patients with clear cell renal cell carcinoma.VDAC inhibition by tubulin and its physiological implications.Cracking the cytotoxicity code: apoptotic induction of 10-acetylirciformonin B is mediated through ROS generation and mitochondrial dysfunctionAuto-antibodies to β-F1-ATPase and vimentin in malignant mesotheliomaATP/ADP ratio, the missed connection between mitochondria and the Warburg effect.Enriched environment inhibits mouse pancreatic cancer growth and down-regulates the expression of mitochondria-related genes in cancer cells.Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate.Autophagy inhibitor LRPPRC suppresses mitophagy through interaction with mitophagy initiator Parkin.Proteomic and functional profiles of a follicle-stimulating hormone positive human nonfunctional pituitary adenoma.Quantitative LC-MS/MS Analysis of Proteins Involved in Metastasis of Breast Cancer.Transcriptomic profiling of host-parasite interactions in the microsporidian Trachipleistophora hominisMild Alkalization Acutely Triggers the Warburg Effect by Enhancing Hexokinase Activity via Voltage-Dependent Anion Channel BindingThe Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology.Phaeochromocytoma: a catecholamine and oxidative stress disorder.Energy metabolism in nuclear reprogrammingVDAC1: from structure to cancer therapy.Relevance of mitochondrial genetics and metabolism in cancer development.Mitochondrial uncoupling and the reprograming of intermediary metabolism in leukemia cells.Dibenzophenanthridines as inhibitors of glutaminase C and cancer cell proliferation.Clinical implication of voltage-dependent anion channel 1 in uterine cervical cancer and its action on cervical cancer cells.Manganese superoxide dismutase deficiency triggers mitochondrial uncoupling and the Warburg effect.Current state of theoretical and experimental studies of the voltage-dependent anion channel (VDAC)An integrated multidisciplinary model describing initiation of cancer and the Warburg hypothesis.Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancerATP increases within the lumen of the endoplasmic reticulum upon intracellular Ca2+ release.Mitochondria play an important role in the cell proliferation suppressing activity of berberine.Mammalian NADH:ubiquinone oxidoreductase (Complex I) and nicotinamide nucleotide transhydrogenase (Nnt) together regulate the mitochondrial production of H₂O₂--implications for their role in disease, especially cancer.Mitochondrial regulation of cell cycle and proliferation.3-Bromopyruvate: targets and outcomes.Deregulation of glycolysis in cancer: glyceraldehyde-3-phosphate dehydrogenase as a therapeutic target.Interferon-γ-induced necrosis: an antitumor biotherapeutic perspective.Mitochondrial channels: ion fluxes and more.Metabolic isoenzyme shifts in cancer as potential novel therapeutic targets.The mitochondrial permeability transition pore and its adaptive responses in tumor cells.Hallmarks of Pulmonary Hypertension: Mesenchymal and Inflammatory Cell Metabolic Reprogramming.Elevated levels of mitochondrion-associated autophagy inhibitor LRPPRC are associated with poor prognosis in patients with prostate cancer.ATP/ADP Turnover and Import of Glycolytic ATP into Mitochondria in Cancer Cells Is Independent of the Adenine Nucleotide Translocator.Differentiation of human neuroblastoma cells toward the osteogenic lineage by mTOR inhibitor
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The pivotal roles of mitochondria in cancer: Warburg and beyond and encouraging prospects for effective therapies.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 08 April 2010
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
The pivotal roles of mitochond ...... pects for effective therapies.
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The pivotal roles of mitochond ...... pects for effective therapies.
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type
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The pivotal roles of mitochond ...... pects for effective therapies.
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The pivotal roles of mitochond ...... pects for effective therapies.
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The pivotal roles of mitochond ...... pects for effective therapies.
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The pivotal roles of mitochond ...... pects for effective therapies.
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P2093
P2860
P1476
The pivotal roles of mitochond ...... pects for effective therapies.
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P2093
Peter L Pedersen
Saroj P Mathupala
Young H Ko
P2860
P304
P356
10.1016/J.BBABIO.2010.03.025
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P577
2010-04-08T00:00:00Z